2010
DOI: 10.1186/1471-2377-10-1
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Clinical profile of parkinsonism and Parkinson's disease in Lagos, Southwestern Nigeria

Abstract: BackgroundCurrent data on the pattern of parkinsonism and Parkinson's disease in Nigerians are sparse.This database was designed to document the clinical profile of PD in Nigerians, and compare this to prior observations.MethodsA database of patients presenting to the Neurology out-patients clinic of the Lagos University Teaching Hospital was established in October 1996. Demographic and clinical data at presentation (disease stage using Hoehn and Yahr scale; 'off' state severity on the Unified Parkinson's dise… Show more

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Cited by 85 publications
(106 citation statements)
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“…Majority of the ADRs (71.1%) were "mild level 1", 20.9% "moderate level 3" and 8% "mild level 2" severity. 1,16 Moderate level 3 ADRs included dyskinesia, blurred vision, hallucination, dystonia, chorea, depression, facial tics and akathisia. Mild level 2 ADRs included freezing attacks and mental confusion.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Majority of the ADRs (71.1%) were "mild level 1", 20.9% "moderate level 3" and 8% "mild level 2" severity. 1,16 Moderate level 3 ADRs included dyskinesia, blurred vision, hallucination, dystonia, chorea, depression, facial tics and akathisia. Mild level 2 ADRs included freezing attacks and mental confusion.…”
Section: Resultsmentioning
confidence: 99%
“…1 Symptoms correlate with the site of affection of susceptible nerve cells and spread of pathological process in the brain. 2,3 The choice of drug depends on whether it is tremor dominant or akineto-rigid parkinsonism, age of onset and presence of comorbidities.…”
Section: Introductionmentioning
confidence: 99%
“…Elevated levels of p -Akt, as well as one of its downstream signaling molecules, phosphorylated glycogen synthase kinase 3 beta ( p -GSK3β), have been observed at 1.5 and 24 h post-FUS (Jalali et al, 2010). Although the Akt pathway has been implicated in increased BBB permeability following focal cerebral ischemia (Kilic et al, 2006), there have been no causal links established between increased p -Akt immunoreactivity and FUS-induced BBBO.…”
Section: Biological Mechanisms Of Focused Ultrasound and Microbubbmentioning
confidence: 99%
“…Tropical Gastroenterology 2014;35 (4): [227][228][229][230][231] 2005. It was projected that the burden of PD would double by 2030.…”
Section: © Tropical Gastroenterology 2014mentioning
confidence: 99%