Clinical Profile of Subclinical Hypothyroidism:A Retrospective Study

Shetty, Meenakshi; Adiraju, Krishna Prasad; Modugu, Nageswar Rao

doi:10.18311/ijmds/2017/18835

Cited by 2 publications

(9 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These studies reported prevalence of subclinical hypothyroidism in the range of 8 to 9%. 5,6,16 Majority of the patient in the present study were in extremes i.e. 21-30 and >51 years.…”

Section: Discussionmentioning

confidence: 69%

“…Such studies have been tried in other parts of the world. 5,6,14 Precisely, the absence or minimally present mild symptoms makes the diagnosis of subclinical hypothyroidism challenging, which is not the case with frank hypothyroidism. 10% of the patients in the present study had no symptoms, while 40% has vague generalized fatigue which generally associated with number of diseases and can be attributed to hectic lifestyle.…”

Section: Discussionmentioning

confidence: 99%

“…This finding was in contrast to that of study done by Shetty et al, which reported maximum affected age group as 31-40 years. 5 Nevertheless, demographic distribution of subclinical hypothyroidism will help to screen these age group subjects more vigorously. This is important, as screening that focuses on vulnerable population is likely to detect disease more frequently and timely intervention will reduce the chances of overt disease.…”

Section: Discussionmentioning

confidence: 99%

“…17 Prevalence in females was double as compared to males in the present study, which is in corroboration to findings of other studies. 5,17,18 Subclinical hypothyroidism has numerous complications on female fertility, maternal and fetal outcomes in pregnancy. It has been cited in many studies that incidence of subclinical hypothyroidism escalates with advancing age.…”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4] The prevalence in India, as gathered from various clinical and epidemiological studies ranges from 6 to 15%. 5 A major chunk of patients with SCH are at greater risk of suffering from frank hypothyroidism. Thus, it is quite logical to anticipate that regular and mass screening of patients to detect SCH will help the overall prevalence of overt hypothyroidism.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

A clinico-epidemiological analysis of subclinical hypothyroidism in a tertiary care health center

2019

View full text Add to dashboard Cite

Background: Subclinical hypothyroidism (SCH) is defined by increase in serum thyroid stimulating hormone (TSH) and free thyroxine (FT4) and free triiodothyronine (FT3) levels within normal range, coupled with absence of typical clinical symptoms. The present study was undertaken to analyse the SCH associated comorbidities, especially lipid disturbances, thyroid autoantibodies, etc.Methods: The present study was retrospective observational study, which was carried out at a tertiary health care center.Results: Out of the 100 patients, majority were in the age group 21 to 30 years (31 patients), followed by 26 patients in age group >51 years and least in age group 41 to 50 years. Prevalence showed female predilection, with female: male ratio of 1.9:1. Most common symptom reported was general fatigue, which was encountered in 40 patients, followed by weight gain, menstrual abnormalities, and constipation. 10 patients were asymptomatic. Serum TSH range in the patients was 5 to 21.1 µIU/l, while mean TSH was 10.9 µIU/l. 20 patients were found to have serum TSH>10.Conclusions: Despite high prevalence, detection rate of subclinical hypothyroidism is very low. Carrying out epidemiological study on national scale is need of the hour, as lack of typical clinical features makes the detection less likely and it has numerous complications, if untreated.

show abstract

“…These studies reported prevalence of subclinical hypothyroidism in the range of 8 to 9%. 5,6,16 Majority of the patient in the present study were in extremes i.e. 21-30 and >51 years.…”

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A clinico-epidemiological analysis of subclinical hypothyroidism in a tertiary care health center

2019

View full text Add to dashboard Cite

show abstract

Study of clinical profile of hypothyroidism in a tertiary care hospital, Central India

Jain¹,

Sharma²,

Mishra³

2022

ijhs

View full text Add to dashboard Cite

Background: hypothyroidism is a common disorder in overweight Indian female populations. Comorbidities and complications are more in patients with hypothyroidism compared to other people. Hence early diagnosis and early treatment for hypothyroidism can prevent a lot of complications in patients, especially for subclinical hypothyroidism. Aim and Objective: To study the presentation and clinical profile of hypothyroidism in central Indian population. Material &Methods: this cross sectional study was carried out among 240 clinically diagnosed patients of hypothyroidism in a tertiary care centre, Madhya Pradesh, India. Thorough history and clinical examination was done to ascertain the clinical features. Results: females had a higher (71.7%) incidence of hypothyroidism than male. Most common symptoms are of weakness, weight gain, facial puffiness, irritability, hair loss and menstrual irregularities. On general examination most common findings are weight gain, pallor, dry skin, pedal edema and Goiter. Type 2 diabetes mellitus, dyslipidemia, obesity and hypertension were commonly associated with the hypothyroidism. Conclusions: hypothyroidism most common in older age females. Weight gain, weakness, facial puffiness, pedal edema, falling of hair, pallor and menstrual irregularities was the common clinical presentation of hypothyroidism

show abstract

Clinical Profile of Subclinical Hypothyroidism:A Retrospective Study

Abstract: ABSTRACT

Cited by 2 publications

References 22 publications

A clinico-epidemiological analysis of subclinical hypothyroidism in a tertiary care health center

A clinico-epidemiological analysis of subclinical hypothyroidism in a tertiary care health center

Study of clinical profile of hypothyroidism in a tertiary care hospital, Central India

Contact Info

Product

Resources

About