Clinical Profiles and Patterns of Kidney Disease Progression in C3 Glomerulopathy

Abstract

on behalf of the Spanish Group for the Study of Glomerular Diseases (GLOSEN) Key Points c Kidney survival in C3 glomerulopathy is significantly higher in patients with a disease chronicity score ,4 and proteinuria ,3.5 g/d, regardless of baseline eGFR. c A faster eGFR decline in C3 glomerulopathy is associated with higher probability of kidney failure. c Patients with glomerulopathy with a progressive reduction in proteinuria over time did not reach kidney failure.

Iptacopan in Idiopathic Immune Complex–Mediated Membranoproliferative Glomerulonephritis: Protocol of the APPARENT Multicenter, Randomized Phase 3 Study

“… 38 The same group has reported that in patients with C3G, a faster rate of decline in eGFR is associated with a higher probability of kidney failure. 16 …”