Clinical profiles, electrolytes status in acute strokes and their outcome

Pradhan, B. B.; Majhi, Chakradhar; Panigrahi, Sunil K.

doi:10.18203/2349-3933.ijam20181446

Cited by 5 publications

(2 citation statements)

References 13 publications

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“…Pradhan et al [ 11 ] showed that out of 64 patients from 100, diagnosed for ischemic stroke, only six developed a change in sodium level with a mean level coming out to be 136 mMol/L. Our study displayed 33 out of 132 identified ischemic stroke patients developing hyponatremia with their sodium levels in the range of 130 mMol/L to 134 mMol/L.…”

Section: Discussionmentioning

confidence: 45%

Evaluation of Hyponatremia in Ischemic Stroke Patients in a Tertiary Care Hospital of Karachi, Pakistan

Mahesar

Memon

Mustafa

et al. 2019

Cureus

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IntroductionElectrolyte disturbances are commonly found in acute stroke settings. Hypernatremia, hyponatremia and hypokalemia are the commonest types of electrolyte disturbances. Data on electrolyte changes in neurological disorders like stroke is insufficient in Asia. This study aims to quantify the decrease in sodium levels in patients of ischemic stroke and to see whether the presence of co-morbidities like hypertension and diabetes result in decrement in the sodium level of the patients admitted.MethodologyThis is a cross-sectional study conducted in Ruth M Pfau Civil hospital Karachi on 132 consenting patients diagnosed with ischemic stroke on a clinical and radiological basis using a preformed questionnaire with all the necessary information to evaluate the objective like gender, level of sodium and co-morbidities. The data was analyzed using Chi‑squared test using SPSS (Statistical Package for Social Science) software version 22 (IBM, NY, USA).ResultThe study showed that the majority of the patients (25%) had mild hyponatremia (130-134 mMol/L), only a few (9.8%) had moderate (125-129 mMol/L) or profound (<125) hyponatremia (3.8%) and 17 out of 44 patients who were hypertensive had their sodium levels changed while only 10 out of 17 diabetics had fluctuating sodium levels (p-value = 0.00). We also found out that most of the patients with altered sodium levels were male in the age range of above 55.ConclusionPatients with ischemic stroke do develop hyponatremia, but only with a slight alteration in the sodium levels.

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Section: Discussionmentioning

confidence: 45%

Evaluation of Hyponatremia in Ischemic Stroke Patients in a Tertiary Care Hospital of Karachi, Pakistan

Mahesar

Memon

Mustafa

et al. 2019

Cureus

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“…The results were comparable to our study. Pradhan et al showed that mean sodium in the hemorrhagic group was lower than that in the ischemic group [12].…”

Section: Discussionmentioning

confidence: 99%

Clinical Spectrum of Hyponatremia in Patients with Stroke

Ehtesham¹,

Mohmand²,

Raj³

et al. 2019

Cureus

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IntroductionHyponatremia is a common electrolyte imbalance, which is readily observed in patients with ischemic as well as hemorrhagic stroke. It is mostly hypoosmolal and may be due to syndrome of inappropriate anti-diuretic hormone (SIADH) or cerebral salt wasting syndrome (CSWS). The aim of this study was to evaluate the clinical spectrum of hyponatremia in patients of both hemorrhagic and ischemic strokes.MethodsIn this prospective observational study, all patients admitted with stroke were screened for serum sodium levels right after hospital admission. Patients with serum sodium levels <135 mEq/L were included. Their demographic characteristics, type of stroke, etiology of hyponatremia, and site of hemorrhage/vascular territory ischemia was included.ResultsHyponatremia was diagnosed in 34.2% of patients. Their mean serum sodium level was 130.4 ± 3.5 (mEq/L). Ischemic stroke was more common in the hyponatremia group (67.7%), and SIADH was a more common cause of hyponatremia (71.1%). In hyponatremic patients with hemorrhagic stroke, right putamen hemorrhage was seen in 50% of patients with SIADH, and right thalamus was seen in 73.3% patients with CSWS. In hyponatremic patients with ischemic stroke, left middle cerebral artery ischemia was seen in 47% patients with SIADH and right middle cerebral artery ischemia was seen in 55% patients with CSWS.ConclusionIn patients with hyponatremia secondary to stroke, ischemic stroke is a common entity. SIADH remains a more frequently witnessed underlying pathology in hyponatremic stroke patients.

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Stress hyperglycemia and electrolytes disturbance in patients with acute cerebrovascular stroke

El-Fawal

Badry

Abbas

et al. 2019

Egypt J Neurol Psychiatry Neurosurg

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Background Stroke is a medical emergency and considered the 2nd leading cause of mortality worldwide. High morbidity and mortality of stroke are due to some complications like cerebral edema, infection, and associated heart disease. Stroke may cause stress hyperglycemia and electrolyte disturbance that may be independent predictors for increased morbidity and mortality. Data on electrolyte disorder in neurological conditions especially acute stroke are somewhat scanty and not frequently interpreted. Objectives The current study aimed to evaluate the effect of stress induced by acute stroke on the blood glucose and serum electrolytes and its relationship to the type, severity, and prognosis of stroke. Subjects and methods A total of 100 patients admitted with acute stroke were included in the study. After informed consent, fasting blood sugar, glycosylated hemoglobin, serum sodium, and potassium levels were measured simultaneously. Stroke severity and outcome were assessed using the Glasgow Coma Scale. Results Stress hyperglycemia was noted in 21 patients, out of which 62% presented with hemorrhagic stroke. Undiagnosed diabetes was found in 47% of cases. Also, 13 % of our patients had both stress hyperglycemia and electrolyte disturbance simultaneously. Mortality among hemorrhagic versus ischemic patients was 46% and 22%, respectively. The independent predictors of mortality were stress hyperglycemia, electrolytes disturbance, ischemic heart diseases, and type and admission severity of stroke. Conclusion Stress hyperglycemia and electrolyte disturbance after acute stroke were found in 21% and 47% of patients respectively and may adversely affect outcome of stroke especially those with cerebral hemorrhage.

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Clinical profiles, electrolytes status in acute strokes and their outcome

Cited by 5 publications

References 13 publications

Evaluation of Hyponatremia in Ischemic Stroke Patients in a Tertiary Care Hospital of Karachi, Pakistan

Evaluation of Hyponatremia in Ischemic Stroke Patients in a Tertiary Care Hospital of Karachi, Pakistan

Clinical Spectrum of Hyponatremia in Patients with Stroke

Stress hyperglycemia and electrolytes disturbance in patients with acute cerebrovascular stroke

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