2011
DOI: 10.1179/1465328111y.0000000040
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Clinical profiles of 13 children withPlasmodium vivaxcerebral malaria

Abstract: P. vivax mono-infection can cause cerebral malaria and multi-organ dysfunction.

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Cited by 51 publications
(50 citation statements)
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“…Although P. vivax infection is usually nonfatal, severe complications, including renal failure, severe anemia, and cerebral malaria, have been reported (2)(3)(4)(5)(6)(7)(8)(9)(10)(11). Because infections with P. vivax parasites can recrudesce months or years after the initial infection, the parasites are also more difficult to eliminate from the community.…”
mentioning
confidence: 99%
“…Although P. vivax infection is usually nonfatal, severe complications, including renal failure, severe anemia, and cerebral malaria, have been reported (2)(3)(4)(5)(6)(7)(8)(9)(10)(11). Because infections with P. vivax parasites can recrudesce months or years after the initial infection, the parasites are also more difficult to eliminate from the community.…”
mentioning
confidence: 99%
“…Case reports of severe P. falciparum-like malaria attributed to P. vivax have been published, including several using PCR diagnostics (Tanwar et al 2011;Kochar et al 2007Kochar et al , 2009Kochar et al , 2010Mueller et al 2009). A recent study demonstrated increased BUN to be an independent predictor of child mortality in severe malaria (von Seidlein et al 2012).…”
Section: Discussionmentioning
confidence: 99%
“…Severe and complicated malaria is usually caused by the Plasmodium falciparum parasite, but P. vivax, usually considered a benign parasite that causes disease resulting in low-case fatality rates, can also occasionally cause severe disease. Reported severe manifestations of P. vivax include cerebral malaria, liver dysfunction, acute kidney injury, severe anemia, acute respiratory distress syndrome, shock, abnormal bleeding, and multiple organ failure (Saxena et al 2012;Tanwar et al 2011;Kochar et al 2003, 2005, Joshi et al 2008Anstey et al 2009;Singh et al 2011;Sonkar et al 2011;Choi et al 2004;Chung et al 2008;Prakash et al 2003). The mechanism of P. vivaxassociated acute kidney injury (AKI) and its effective management remain unclear.…”
Section: Introductionmentioning
confidence: 95%
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“…As disease manifestations are significantly different between adults and children these instances are mentioned within the text. Although severe malaria and CM are usually caused by P. falciparum, severe disease caused by infection with Plasmodium vivax has been increasingly reported in Asia, South America and Africa in the past several years [2][3][4][5]. This review will focus on P. falciparum; reviews on the emerging possibility of P. vivax CM are available elsewhere [6].…”
mentioning
confidence: 99%