2019
DOI: 10.1186/s12879-019-4365-9
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Clinical profiles of early and tuberculosis-related mortality in South Korea between 2015 and 2017: a cross-sectional study

Abstract: Background Although the incidence of tuberculosis (TB) has decreased in South Korea, the mortality rate remains high. TB mortality is a key indicator for TB control interventions. The purpose of this study was to assess early and TB-related mortality during anti-TB treatment and describe the associated clinical characteristics. Methods A multicenter cross-sectional study was performed across South Korea. Patients with pulmonary TB who died during anti-TB treatment and w… Show more

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Cited by 24 publications
(22 citation statements)
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“…Furthermore, there have been reports that BMI is inversely associated with the risk of TB [24]. Obesity presented a protective effect, while a lower BMI was associated with the development of TB [25] and higher TB-related mortality [26]. However, BMI is also associated with metabolic syndrome such as diabetes mellitus [27], so these opposite effects of BMI could confuse their role in TB [25].…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, there have been reports that BMI is inversely associated with the risk of TB [24]. Obesity presented a protective effect, while a lower BMI was associated with the development of TB [25] and higher TB-related mortality [26]. However, BMI is also associated with metabolic syndrome such as diabetes mellitus [27], so these opposite effects of BMI could confuse their role in TB [25].…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, there have been reports that BMI is inversely associated with the risk of TB (25). Obesity presented a protective effect, while a lower BMI was associated with the development of TB (26) and higher TB-related mortality (27). However, BMI is also associated with metabolic syndrome such as diabetes mellitus (28), so these opposite effects of BMI could confuse their role in TB (26).…”
Section: Discussionmentioning
confidence: 99%
“…The mortality rates of older patients have been reported as up to 51% [7]. Although these mortality rates have been decreasing recently, the rate remains high [8,9]. Moreover, age represents a risk factor connected to the development of adverse drug reactions due to polypharmacy, pill burden, existing co-morbidities, and a lower efficiency of renal and hepatic drugs clearance.…”
Section: Introductionmentioning
confidence: 99%