Clinical Prospects for Neural Grafting Therapy for Hippocampal Lesions and Epilepsy

Etiopathogenesis of Central Nervous System Gliomas

“…In some cerebral areas in case 2, there was a marked reaction of endothelium in the blood vessels [85]. For this reason, I agree with other authors that lowgrade astrocytomas debut with epileptic seizures and they can be cured with surgery [4,7,10,17,85,86]. For example, according to Suarez et al [4], in 24 of 30 children operated on by low-grade brain gliomas, they debuted with epilepsy and in 12 patients the tumor was located in the temporal lobe.…”

“…In my opinion, in addition to aspirin and NSAIDs, the patient must have a high level of hemoglobin, as well as can be supplemented with hyperbaric oxygenation [89] and/or ozone therapy; because the cancer cells are anaerobic (do not breathe oxygen) and cannot survive in presence of high levels of oxygen [58,76,90,91]. Finally, from the neurosurgical point of view, epileptic seizures caused by ischemia or by low-grade astrocytomas can be reduced or aborted; after revascularization of the epileptogenic focus [33, 86,92,93] or removal of the low-grade astrocytoma [4,10,85,94].…”

Computed Tomography-Guided Percutaneous Cordotomy

“…A number of previous authors 34, 35 have pointed out that this procedure has been reported by Rafael in letters to journal editors to be an excellent treatment for a wide variety of disease, without an underlying mechanism having been demonstrated. 16,[34][35][36][37][38][39][40][41][42] The clinical results observed by Rafael would be strengthened by further studies of omental tissue transplantation in animals, image confirmed alterations in local perfusion with vascular studies such as SPECT scan or angiography, post-mortem pathological investigation, and analysis of local vascular protein expression. Without angiographic follow-up, the theoretical benefits of posterior fossa omental grafts are difficult to rationalize or support.…”