Clinical, radiographical and histological evaluation of alveolar ridge preservation with an autogenous tooth derived particulate graft in EDS class 3–4 defects

Abstract

Background The shrinkage of alveolar bone dimensions after tooth extraction is a well-known issue. This clinical phenomenon poses a challenge for clinicians aiming at implant-prosthetic treatment. BonMaker® ATB is a novel autogenous bone grafting material, produced by the mechanical and chemical processing of natural teeth. This pilot case report aims at providing a clinical, radiographical, and histological evaluation of the safety and efficacy of Bonmaker ATB powder in the treatment of EDS class 3–4 postextraction sockets with alveolar ridge preservation. Methods A total of 9 teeth were extracted from 5 patients. The extracted teeth were prepared immediately with the Bonmaker® device. The extraction sockets were filled up with ATB powder. Six months after extraction, standardized intraoral x-rays and CBCT scans were performed. Re-entry was performed under local anaesthesia. Core biopsies were harvested for histological analysis and implants were placed. Results Horizontal alveolar dimension loss occurred, even though ARP was performed, but the horizontal shrinkage was moderate. Vertical dimensions did not show loss of volume, but increased defect fill. Core biopsies showed ATB particles surrounded by newly formed bone and connective tissue. According to histomorphometric analysis, the harvested samples contained 56% of newly formed bone on average, and only a mean of 7% of non-remodelled ATB material was observed. Conclusion The preliminary clinical, radiographical, and histological results of Bonmaker® autogenous tooth graft therapy indicate that ATB may be safely and successfully used as a grafting material for ARP. Optimal graft incorporation and histologically proven effective remodelling, as well as uneventful wound healing support the clinical application of ATB to minimize post-extraction hard tissue loss. Further research is needed to exploit the full potential of ATB and to evaluate the long-term peri-implant hard and soft tissue stability of ATB-treated post-extraction sites.

Autogenous Tooth Bone Grafts for Repair and Regeneration of Maxillofacial Defects: A Narrative Review

“…Radoczy-Drajko et al demonstrated that AUTO-BG when used as a graft material for socket preservation leads to a mean bone loss of 15% in the horizontal dimension (maximum at the coronal portion and minimum at the apical) with negligible loss in the vertical dimension. These findings show that successful results can be obtained with AUTO-BG with functional restoration using implants later on [ 86 ].…”

The use of autogenous tooth bone graft powder in the treatment of osseous defects after impacted mandibular third molar extraction: a prospective split-mouth clinical pilot study

“…To date, many studies have confirmed that ATGP could be used as an alternative option, providing excellent biocompatibility without causing an immune response, contagion, or reaction to a foreign material in socket preservation, alveolar repair, and different kinds of bone augmentation in dental clinics [ 15 , 20 – 27 ]. This study reached a similar conclusion.…”

“…(Fig. 1 ) [ 15 ]. The M3 extraction socket was filled and compacted in layers with freshly prepared ATGP.…”

“…Autogenous tooth bone graft materials have demonstrated the ideal characteristics of osteoconductivity, osteoinductivity, and osteogenicity, and these materials produce a nearly gold-standard graft and have low technique sensitivity [ 13 , 18 , 19 ]. BonMaker ® ATB is a novel autogenous bone grafting material produced by the mechanical and chemical processing of natural teeth [ 15 ]. The aim of this pilot study was to introduce a novel method for repairing the distal osseous defects of M2 after the surgical removal of M3 with ATGP.…”

A mandibula és a maxilla vertikális csonthiányainak autológ csontblokkal végzett augmentációja.

“…Napjainkban a dentalis implantátumok, műgyökerek behelyezése, illetve az állcsontok fogmedernyúlványának sorvadása esetén a csont felépítése a fogászati rehabilitáció napi gyakorlatává vált. A fogmedernyúlvány felépítése mind a technikai megoldások, mind a felhasznált csontpótló anyagok és a csontpótlásokat fedő mesterséges membránok szempontjából sokszínű, aktívan kutatott, folyamatosan fejlődő és egyre biztatóbb eredményeket nyújtó terület [1][2][3][4][5]. A felhasznált anyagok fejlődése és sokrétűsége ellenére a mai napig a legtöbben a saját csont alkalmazását tekintik a "gold standard" eljárásnak [6][7][8], ugyanakkor megjegyzendő, hogy Trimmel és mtsai legújabb metaanalízisükben ettől eltérő következtetésre jutottak [9].…”