Clinical, radiologic, demographic, and occupational aspects of hand osteoarthritis in the elderly

Caspi, Dan; Flusser, Gideon; Farber, Irena; Ribak, Joseph; Leibovitz, Arthur; Habot, Beni; Yaron, Michael; Segal, Refael

doi:10.1053/sarh.2001.19957

Cited by 87 publications

(82 citation statements)

References 51 publications

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“…The contribution of age, sex, and handedness in the development of hand OA is one of the interesting questions, with obvious epidemiological importance. Note, for instance, that Chaisson et al (1997) and Caspi et al (2001) reported that while the cumulative incidence of OA was generally higher in women than in men, the joints most frequently affected were the same in both sexes. Nakamura et al (2001) and Jonsson et al (1999) noted a female preponderance in CMC1 joint OA, but they found no clear differences between sexes in DIPs.…”

mentioning

confidence: 99%

“…The main ones are obviously age (Plato and Norris, 1979;Busby et al, 1991;Caspi et al, 2001) and genetic predisposition Livshits et al, 2002). However, the contribution of other factors, particularly sex and handedness, are still under debate (Lane et al, 1989;Chaison et al, 1997;Caspi et al, 2001). The contribution of age, sex, and handedness in the development of hand OA is one of the interesting questions, with obvious epidemiological importance.…”

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confidence: 99%

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Patterns of joint distribution in hand osteoarthritis: Contribution of age, sex, and handedness

Kalichman

Cohen

Kobyliansky

et al. 2004

American J Hum Biol

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The most frequent site of osteoarthritis (OA) is the hands, but the pattern of hand OA development remains controversial. Understanding these patterns may assist in evaluating biological aging, determining etiology, and proposing ways of preventing hand OA. We investigated the pattern distribution of OA in hands and the influences of age, sex, and handedness on its development. The study population was comprised of Chuvashians (660 males age 18-89 years and 585 females age 18-90 years). OA development was evaluated for 15 joints of each hand according to the Kellgren and Lawrence grading scheme. Statistical analyses included Pearson correlation, cluster analysis, MANCOVA, and linear and polynomial regression. OA changes first appeared in subjects <30 years of age. Metacarpophalangeal (MP) joints underwent the first OA changes until the sixth decade, when the row of distal interphalangeal (DIP) joints became most affected. Cluster analysis showed that symmetry was the most common pattern of interrelationship between rows of joints. The best-fitting and most parsimonious model of age-related pattern of hand OA was the polynomial two-interval linear model. It showed a higher rate of OA development during the relatively young ages, 32-34 years than later on. We found statistically significant differences between sexes only for the DIP (P = 0.019) and PIP (P = 0.011) rows of joints. Handedness had no influence on hand OA development.

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confidence: 99%

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confidence: 99%

Patterns of joint distribution in hand osteoarthritis: Contribution of age, sex, and handedness

Kalichman

Cohen

Kobyliansky

et al. 2004

American J Hum Biol

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show abstract

“…[4] Nodüller, osteofit gibi altta yatan yap›sal anormallikler ile ilgilidir. [5][6][7] Bu tipik el OA's› iflaretleri a¤r›, tutukluk, hareket kayb›, azalm›fl kavrama gücü ve hareket k›s›tl›l›¤›na neden olabilmektedir.…”

Section: El Osteoartritinin Tan›s›unclassified

Approach to hand osteoarthritis

Ermurat¹,

Dalkılıç²

2016

RAED Derg

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“…Multiple nodes are regarded widely as a marker for generalized OA (4). Few studies have investigated the association between hand nodes and underlying structure changes (5)(6)(7)(8). In the studies that have investigated this, the measures used to assess the association were inconsistent, which led to a different clinical interpretation of the association.…”

Section: Introductionmentioning

confidence: 99%

“…Other reported risk factors for hand OA include positive family history, obesity, occupation, and prior injury (9). There is conflicting evidence as to whether dominance of the left or right hand affects development of hand OA (5,10,11).…”

Section: Introductionmentioning

confidence: 99%

Distribution of finger nodes and their association with underlying radiographic features of osteoarthritis

Rees¹,

Doherty²,

Hui³

et al. 2012

Arthritis Care & Research

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Objective. To determine the distribution of clinically palpable hand interphalangeal (IP) nodes at each finger and thumb joint in a population with nodes, the influence of left or right hand dominance and sex on the development of nodes, and the association between nodes and underlying radiographic features of osteoarthritis (OA). Methods. We performed a cross-sectional analysis of participants in the Genetics of Osteoarthritis and Lifestyle (GOAL) study who had >1 Heberden's nodes or Bouchard's nodes on clinical examination. Frequencies (%) of nodes were described for each IP joint in the hand. Associations between nodes and underlying radiographic OA were shown with odds ratios (ORs) and 95% confidence intervals. A logistic regression model was used to adjust for the following confounding factors: age, sex, body mass index, left or right hand dominance, hand trauma, occupation with heavy manual activity, and participation in sports. Results. Of the 3,170 GOAL participants, 1,939 had >1 nodes (mean age 68 years, 54% women). The distal IP joints of the index finger were the most frequently affected, followed by the thumb IP joint. Nodes were more common in dominant hands and women. There was a significant association between nodes and underlying radiographic OA (OR range 2.26 -21.23). This association was stronger for joint space narrowing than for osteophytes. A dose-response relationship was found between clinical severity of Heberden's nodes and underlying radiographic change. Conclusion. Our study supports the positive association between nodes and radiographic OA, especially narrowing, and the influence of sex and left or right hand dominance on development of nodes. In this age group, presence of nodes may be taken as an indication of underlying small joint OA.

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Clinical, radiologic, demographic, and occupational aspects of hand osteoarthritis in the elderly

Cited by 87 publications

References 51 publications

Patterns of joint distribution in hand osteoarthritis: Contribution of age, sex, and handedness

Patterns of joint distribution in hand osteoarthritis: Contribution of age, sex, and handedness

Approach to hand osteoarthritis

Distribution of finger nodes and their association with underlying radiographic features of osteoarthritis

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