Clinical, radiological, and pathological features of 16 papillary glioneuronal tumors

Abstract

PGNTs displayed a wide spectrum of clinical and radiological phenotypes, and they were more frequently observed in the frontal lobe and in young patients without sex predilection. Fair outcomes could be achieved by complete resection. Although PGNT displayed indolent pathobiology, atypical appearances were observed. More patients and longer follow-up periods are needed to further elucidate the biological features of PGNTs.

Epilepsy-associated tumours: what epileptologists should know about neuropathology, terminology, and classification systems

“…a fragment containing just one of the pathological cell elements of this tumour type (Louis et al ., ; Prayson, ). PGNTs, RGNTs, GNTNIs, and angiocentric gliomas may not always be classified correctly because they are so rare and have been described only recently (Li et al ., ).…”

Papillary Glioneuronal Tumour: A Case Report

“…PGNT predominantly affects the younger population as the patients’ age varied from 11 to 41 years in the series reported by Li et al [10]. The presenting symptoms of PGNT were related to increased intracranial pressure, seizures, focal neurological symptoms associated with tumour localization including hemiparesis, dysphasia, or visual disturbances [1, 6, 8-12].…”

“…Neuroimaging usually shows a cyst lesion with the most frequent pattern being a cystic and solid tumour or cystic tumour with mural nodule [1, 9, 13]. Purely cystic and solid tumour cases were less common [10, 14]. Cystic components are often hypointense on T1WI and hyperintense or isointensive on T2WI views.…”

“…The tumour has been assigned to a grade I, however, a few aggressive behavior variants have been also reported [5-7]. To our knowledge, about 100 cases of PGNT have been described in the literature, but only a few patients with predominantly focal neurological deficits were reported [8-10]. We report on the clinical, radiological, and histopathological features of an additional example of PGNT.…”

Gliom Disi Intra-Aksiyal Beyin Tumorleri

“…Gençlerde kafa içi basınç artışı bulguları ile görülen WHO evre I tümördür [1]. Nadiren tümör içi kanama ve peritümöral ödem gösterebilen tümör, frontal ve temporal lobları sıklıkla tutarken, subependimal ve intraventriküler yerleşimde gösterebilir [10]. Tipik olarak kistik, solid veya kist içinde opaklaşan mural nodül şeklinde izlenen tümör (Resim 4), sıklıkla ganglioglioma olarak raporlanır ve ayırıcı tanısını sağlayan belirgin bir radyolojik ölçüt yoktur [10][11][12].…”