arly mobilization (EM) is a commonly used intervention for critically ill patients, which involves progressive functional mobility that is initiated as soon as medically feasible. 1 Despite guidelines for the initiation of EM, challenges to mobilizing intensive care unit (ICU) patients continue to affect patient care; some of these include lack of adequate staffing and equipment, line placement and management, sedative practices, and hemodynamic instability. [2][3][4] Common interventions associated with EM include sitting upright in bed, sitting out of bed in a chair, standing activities, and ambulation. 1,5 EM appears effective at reducing ICUacquired weakness, shortening the time on mechanical ventilation, and improving functional capacity. 6 Patients with severe cardiac and/or pulmonary failure may require mechanical circulatory support (MCS), which is used to maintain adequate circulation and respiratory function. Patients on MCS are typically candidates for EM when medically feasible. 5,7 Extracorporeal membrane oxygenation (ECMO) and ventricular assist devices (VADs) are examples of MCS device categories. 8 Use of MCS devices is becoming more common; the use of ECMO alone has increased 3-fold in the United States from the year 2010 to 2019. 9 A variety of cannulation sites and circuit configurations can be used to individualize the support provided to the patient; however,