Clinical research as a critical component of epidemic response: the case of PREVAIL in Liberia

Fallah, Mosoka; Lane, H. Clifford; Higgs, Elizabeth; Kennedy, Stephen B.; Massaquoi, Moses; Kieh, Mark; Neaton, James D.; Hensley, Lisa E.; McNay, Laura A.; Njoh, Wissedi; Doe-Anderson, Jestina W.

doi:10.1016/s2214-109x(23)00040-2

The Lancet Global Health

2023

DOI: 10.1016/s2214-109x(23)00040-2

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Clinical research as a critical component of epidemic response: the case of PREVAIL in Liberia

Mosoka Fallah¹,

H. Clifford Lane²,

Elizabeth Higgs³

et al.

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Translational success of fundamental virology: a VSV-vectored Ebola vaccine

Anderson,

Coller

2024

J Virol

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Ebola virus disease (EVD) caused by Ebola virus (EBOV) is a severe, often fatal, hemorrhagic disease. A critical component of the public health response to curb EVD epidemics is the use of a replication-competent, recombinant vesicular stomatitis virus (rVSV)-vectored Ebola vaccine, rVSVΔG-ZEBOV-GP (ERVEBO). In this Gem, we will discuss the past and ongoing development of rVSVΔG-ZEBOV-GP, highlighting the importance of basic science and the strength of public-private partnerships to translate fundamental virology into a licensed VSV-vectored Ebola vaccine.

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Translational success of fundamental virology: a VSV-vectored Ebola vaccine

Anderson,

Coller

2024

J Virol

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We must revise the current logic to protect our humanity from infectious disease outbreaks

Fallah

2023

J. Public Health Afr.

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Clinical research as a critical component of epidemic response: the case of PREVAIL in Liberia

Cited by 2 publications

References 6 publications

Translational success of fundamental virology: a VSV-vectored Ebola vaccine

Translational success of fundamental virology: a VSV-vectored Ebola vaccine

We must revise the current logic to protect our humanity from infectious disease outbreaks

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