Purpose: To compare the postoperative outcomes between Akreos MI60 and Akreos AO intraocular lens (IOLs) after cataract surgery. Methods: A prospective analysis among 55 eyes of 55 patients who had undergone microcoaxial phacoemulsification and implantation of aspheric IOLs (Akreos MI60, 30 eyes; Akreos Adapt-AO, 25 eyes) was performed. The best corrected visual acuity (BCVA), spherical equivalent, intraocular pressure (IOP), corneal thickness, endothelial cell density (ECD), surgically induced astigmatism (SIA), predictability of postoperative spherical equivalent, higher order aberrations, and contrast sensitivity test were evaluated during the follow-up period of 3 months. Results: There were no significant differences in BCVA, spherical equivalent, IOP, corneal thickness, ECD, SIA, higher order aberrations and contrast sensitivity test (p>0.05). The predictability of postoperative spherical equivalent in the Akreos Adapt-AO (-0.57±0.22D) represented statistically significant myopic shift compared with the Akreos MI60 group (-0.05±0.69D) (p=0.02). Conclusions: Both the Akreos MI60 and the Akreos Adapt-AO implantation groups performed similiarly, following cataract surgery, showed similar visual function.