Clinical results of AcrySof intraocular lens implantation

Mengual, Encarna; García, Juan A Lugo; Elvira, Juan Carlos; Hueso, José Ramón

doi:10.1016/s0886-3350(98)80083-7

Cited by 22 publications

(6 citation statements)

References 4 publications

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“…The Nd:YAG laser capsulotomy rate is considerably lower with Acrysof ® IOLs (Alcon Laboratories Inc.) than other IOL lens materials. 17 – 19 , 23 – 26 The Acrysof ® IOLs are a series of acrylic, foldable, hydrophobic, single-, and multi-piece lenses with established clinical performance and safety for over two decades. 17 – 19 , 23 – 28 AcrySof ® IOLs are very stable, have high fibronectin binding, and provide enhanced capsular adhesion, thus providing maximal IOL optic-posterior capsule contact acting as an excellent barrier to prevent cellular proliferation.…”

Section: Discussionmentioning

confidence: 99%

“…5 , 12 In addition, the AcrySof ® IOLs present minimal to absent Soemmering’s ring formation (precursor to PCO development), PCO and anterior capsular opacification, decentration, and minimal tilt. 5 , 26 , 28 In a 7-year follow-up study, the cumulative Nd:YAG laser posterior capsulotomy rate after implantation of AcrySof ® IOLs was observed to be ~1%–2% of new cases per year, reaching a plateau at 6 years. 27 In the present study, the posterior capsulotomy rates with Clareon ® -based IOL Model MA60NM was <1.5% during the 3-year period, which is closer to the lower end of the range of 0%–10% reported in studies with AcrySof ® IOLs during 2- to 5-year follow-up period.…”

Section: Discussionmentioning

confidence: 99%

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Long-term effectiveness and safety of a three-piece acrylic hydrophobic intraocular lens modified with hydroxyethyl-methacrylate: an open-label, 3-year follow-up study

Maxwell¹,

Suryakumar²

2018

OPTH

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BackgroundClareon® is a new hydrophobic acrylic optic biomaterial designed for enhanced clarity and greater resistance to glistening. The present study evaluated the effectiveness and safety of a three-piece hydrophobic, monofocal intraocular lens (IOL) Model MA60NM, made of this new optic material.MethodsIn this prospective, multicenter, open-label study, eligible patients aged ≥60 years, underwent a unilateral implantation with IOL Model MA60NM following phacoemulsification. Patients were followed-up for up to 3 years after implantation. Visual outcome and serious adverse events (SAEs, cumulative and persistent) were compared to ISO grid rates (BS EN ISO 11979-7:2006). The primary effectiveness variable was Best Spectacle-Corrected Visual Acuity (BSCVA) at 1-year postoperative follow-up. In addition, posterior capsular opacification (PCO) was assessed qualitatively and graded by slit lamp exam on a 5-point scale at all visits.ResultsOverall, 179 and 138 patients completed the 1-year and 3-year postoperative follow-up, respectively. The BSCVA outcomes were better with IOL Model MA60NM than the ISO grid rates with 95.5% of patients at 1 year and 94.2% of patients at 3 years having achieved a BSCVA of 20/40 or better vs 92.5% in ISO grid. The incidence of cumulative or persistent SAEs was lower after Model MA60NM implantation than the ISO grid reference. The incidence of clinically significant PCO was 1.1% at the 1-year and 2.2% at the 3-year visit. Posterior capsulotomy rate was 1.1% at 1 year and 1.4% at 3 years.ConclusionThe three-piece hydrophobic, monofocal IOL Model MA60NM was effective for the visual correction of aphakia and successfully met all the safety parameters as defined by the ISO criteria. PCO and posterior capsulotomy rates were low over the 3-year follow-up period. This study provides evidence and supports the long-term safety and effectiveness of the new optic biomaterial Clareon®.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Long-term effectiveness and safety of a three-piece acrylic hydrophobic intraocular lens modified with hydroxyethyl-methacrylate: an open-label, 3-year follow-up study

Maxwell¹,

Suryakumar²

2018

OPTH

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“…This lens has been widely accepted and has played a prominent part in cataract surgery since its introduction in 1994, 1 2 because of stable clinical results [3][4][5] and a low incidence of posterior capsule opacification. [6][7][8][9][10][11] The optic geometry [12][13][14][15] and strong adhesion to the posterior capsule 16 17 are important factors contributing to successful clinical records.…”

mentioning

confidence: 99%

A prospective, randomised comparison of single and three piece acrylic foldable intraocular lenses

Nejima

Miyata²,

Honbou³

et al. 2004

British Journal of Ophthalmology

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Aims: To compare the postoperative performance of single and three piece acrylic foldable intraocular lenses (IOLs). Methods: 20 patients underwent bilateral cataract surgery with a single piece SA30AL IOL in one eye and a three piece MA30BA IOL in the other eye. The eyes were randomly assigned to either a single or three piece lens. The amount of IOL decentration and tilt, area of anterior capsule opening, and degree of posterior capsule opacification were measured using the Scheimpflug anterior segment analysis system (Nidek EAS-1000). Visual acuity and contrast sensitivity were examined. Measurements were performed by masked examiners before and 1 day, 1 week, 1, 3, 6, and 18 months after surgery. Results: There were no significant differences between the two groups (p.0.05, paired t test) in the amount of IOL decentration, IOL tilt, area of anterior capsule opening, degree of posterior capsule opacification, best corrected visual acuity, and contrast sensitivity throughout the 18 month follow up period. Conclusion: The single and three piece acrylic foldable IOLs are equally stable in the eye after surgery.

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“…Since its introduction in 1994, the AcrySof lens (Alcon), has played a prominent role in the popularization of foldable hydrophobic acrylic IOLs 8 . It provides satisfactory surgical results 9,10 except for the only drawback being postoperative glare seen in a portion of the patients 11 . The AF‐1 (model VA60BB), another foldable hydrophobic acrylic IOL, was introduced in Japan in 2001.…”

Section: Discussionmentioning

confidence: 99%

Unfolding characteristics of a new hydrophobic acrylic intraocular lens, and possible association with complications in triple procedures

Iwase

Tanaka

2007

Clinical Exper Ophthalmology

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Clinical results of AcrySof intraocular lens implantation

Abstract: Implantation of AcrySof IOLs did not result in complications or adverse reactions in our series, indicating that its use is safe in small incision cataract surgery.

Cited by 22 publications

References 4 publications

Long-term effectiveness and safety of a three-piece acrylic hydrophobic intraocular lens modified with hydroxyethyl-methacrylate: an open-label, 3-year follow-up study

Long-term effectiveness and safety of a three-piece acrylic hydrophobic intraocular lens modified with hydroxyethyl-methacrylate: an open-label, 3-year follow-up study

A prospective, randomised comparison of single and three piece acrylic foldable intraocular lenses

Unfolding characteristics of a new hydrophobic acrylic intraocular lens, and possible association with complications in triple procedures

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