Clinical Results of Penile Prosthesis Implantation for Treating Organic Erectile Dysfunction

Abstract

Erectile dysfunction (ED) is the second most common sexual dysfunction in men after premature ejaculation (1) and is defined as "the inability of a man to have and/or maintain adequate penile erection for sexual intercourse for at least 6 months" (2). In a community-based study conducted by the Turkish Society of Andrology on the prevalence of ED, its prevalence was found to be 69.2% (33.2% as mild, 27.5% as moderate, and 8.5% as advanced ED) (3). According to the findings of the Massachusetts Male Aging Study (MMAS), which is accepted to be a reference as one of the most important international epidemiological studies, of male patients between the ages of 40 and 70 years, 17% had mild ED, 25% had moderate ED, and 10% had severe ED (4). Based on these findings, it is estimated that the number of ED patients will increase to approximately 322 million worldwide in 2015 (5). It has been demonstrated that frequent ED can seriously affect the quality of life of the spouse as well as the patient (4).In basic scientific and clinical studies conducted on the physiology and pathophysiology of erection, it has been revealed that ED is a vascular pathology associated with risk factors, such as cardiovascular diseases, hypertension, atherosclerosis, lipid disorders, smoking, diabetes mellitus, obesity, metabolic syndrome, and a sedentary lifestyle (2, 6). Apart from the abovementioned medical problems, iatrogenic factors, such as pelvic surgeries, particularly radical prostatectomy where even bilateral neuroprotective is applied, are also among the important factors that play a role in the occurrence of ED (7).Currently, lifestyle changes and primary and secondary care conservative therapies, including medical treatment choices applied orally or through intracavernous injection, are the first techniques performed for patients with ED. Phosphodiesterase type-5 inhibitors, intracavernous injections, intraurethral alprostadil, and vacuum devices can fail in approximately 80% of patients because they discontinue the treatment (8, 9). In such a situation or in ED patients, particularly in the case of ED with an organic origin, with no adequate response to the treatment, despite invasive and costly intervention, flexible or inflatable penile prosthesis implantation, which has been The Clinical Results of Penile Prosthesis Implantation for the Treatment of Organic Erectile DysfunctionIntroduction: The aim of this study is to evaluate the clinical results of penile prosthesis implantation for the treatment of the patients with organic erectile dysfunction (ED).Methods: Medical records of penile prosthesis implantation for the treatments of 36 patients with organic ED between January 2006 and December 2014 were retrospectively reviewed. The demographic data of the patients, the causes and duration of ED, operative time, hospitalization time, types of prosthesis, and intraoperative and postoperative complications were evaluated. Results:The mean age of patients was 53.94±9.66 years and the mean body mass index of the patients was 27....