Clinical results with the model 1IRP implant

Humayun, Mark S.; Yanai, D.; Greenberg, R.J.; Little, Jeffrey P.; Mech, B.V.; Mahadevappa, Manjunatha; Weiland, James D.; Fujii, Gildo Y.; Juan, Eugene de

doi:10.1109/ijcnn.2004.1379853

Cited by 5 publications

(5 citation statements)

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“…In order to simulate the visual perception in prosthetic vision, our phosphenes generated are idealized representations of the percepts feasible in the current implants [45,[65][66][67][68]. For the generation of phosphenes we start from the final image that is shown by the viewfinder (see appendix A).…”

Section: Ethical Statementmentioning

confidence: 99%

Influence of field of view in visual prostheses design: Analysis with a VR system

Sanchez-Garcia¹,

Martínez-Cantín²,

Bermúdez-Cameo³

et al. 2020

J. Neural Eng.

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Objective. Visual prostheses are designed to restore partial functional vision in patients with total vision loss. Retinal visual prostheses provide limited capabilities as a result of low resolution, limited field of view and poor dynamic range. Understanding the influence of these parameters in the perception results can guide prostheses research and design. Approach. In this work, we evaluate the influence of field of view with respect to spatial resolution in visual prostheses, measuring the accuracy and response time in a search and recognition task. Twenty-four normally sighted participants were asked to find and recognize usual objects, such as furniture and home appliance in indoor room scenes. For the experiment, we use a new simulated prosthetic vision system that allows simple and effective experimentation. Our system uses a virtual-reality environment based on panoramic scenes. The simulator employs a head-mounted display which allows users to feel immersed in the scene by perceiving the entire scene all around. Our experiments use public image datasets and a commercial head-mounted display. We have also released the virtual-reality software for replicating and extending the experimentation. Main results. Results show that the accuracy and response time decrease when the field of view is increased. Furthermore, performance appears to be correlated with the angular resolution, but showing a diminishing return even with a resolution of less than 2.3 phosphenes per degree. Significance. Our results seem to indicate that, for the design of retinal prostheses, it is better to concentrate the phosphenes in a small area, to maximize the angular resolution, even if that implies sacrificing field of view.

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Section: Ethical Statementmentioning

confidence: 99%

Influence of field of view in visual prostheses design: Analysis with a VR system

Sanchez-Garcia¹,

Martínez-Cantín²,

Bermúdez-Cameo³

et al. 2020

J. Neural Eng.

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“…A phosphene is defined as any visual sensation represented as a spot of light in the visual field caused by methods other than stimulation of the visual system by light. Phosphenes can be elicited by mechanical forces [2], magnetic stimulation [3][4][5] or electrical stimulation [6][7][8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, epi-and subretinal implants have been developed [6][7][8][9][10][11][12][13][14][15]. Humayun et al, [6][7][8][9], Mahadevappa et al, [10], Rizzo III et al, [11,12], Klauke et al, [13], Eger et al, [14] and Keserüet al, [15] and recent clinical trials [16,17] have reported that blind patients perceived sensations of spots of light while the retina was electrically stimulated.…”

Section: Introductionmentioning

confidence: 99%

“…Humayun et al, [6][7][8][9], Mahadevappa et al, [10], Rizzo III et al, [11,12], Klauke et al, [13], Eger et al, [14] and Keserüet al, [15] and recent clinical trials [16,17] have reported that blind patients perceived sensations of spots of light while the retina was electrically stimulated. These experiments clearly validated the viability of producing perception of light patterns in blind patients by electrically activating nearby retinal ganglion cells (RGCs).…”

Section: Introductionmentioning

confidence: 99%

“…These experiments clearly validated the viability of producing perception of light patterns in blind patients by electrically activating nearby retinal ganglion cells (RGCs). In recent years, Humayun et al, [7,9], Keserü et al, [15], Dobelle et al, [18,19], Zrenner et al, [20,21], Brindley et al, [22,23] and Hornig et al, [24] have reported the generation of recognizable symbols and simpleshapes from multiple stimulated phosphenes.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Treatise of the Physical Aspects of Phosphenes and Single-Cell Selectivity in Retinal Stimulation

DL¹,

Wh²

2017

IJCNE

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Simulating prosthetic vision: I. Visual models of phosphenes

Chen

Suaning²,

Morley³

et al. 2009

Vision Research

159

138

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With increasing research advances and clinical trials of visual prostheses, there is significant demand to better understand the perceptual and psychophysical aspects of prosthetic vision. In prosthetic vision a visual scene is composed of relatively large, isolated, spots of light so-called "phosphenes", very much like a magnified pictorial print. The utility of prosthetic vision has been studied by investigators in the form of virtual-reality visual models (simulations) of prosthetic vision administered to normally sighted subjects. In this review, the simulations from these investigations are examined with respect to how they visually render the phosphenes and the virtual-reality apparatus involved. A comparison is made between these simulations and the actual descriptions of phosphenes reported from human trials of visual prosthesis devices. For the results from these simulation studies to be relevant to the experience of visual prosthesis recipients, it is important that, the simulated phosphenes must be consistent with the descriptions from human trials. A standardized simulation and reporting framework is proposed so that future simulations may be configured to be more realistic to the experience of implant recipients, and the simulation parameters from different investigators may be more readily extracted, and study results more fittingly compared.

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Clinical results with the model 1IRP implant

Cited by 5 publications

References 0 publications

Influence of field of view in visual prostheses design: Analysis with a VR system

Influence of field of view in visual prostheses design: Analysis with a VR system

A Treatise of the Physical Aspects of Phosphenes and Single-Cell Selectivity in Retinal Stimulation

Simulating prosthetic vision: I. Visual models of phosphenes

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