Objective: We hypothesized that a single value of leukocyte count, on admission might be a helpful predictor to prognosticate the clinical outcome and plan the management (early delivery versus conservative management) in patients presenting with pre term pre-labour rupture of membranes (PPROM).Design: Observational study.Setting: This study was conducted in a tertiary care centre.
Population or sample: 127 pregnancies complicated with PPROM.Method: A novel scoring system was devised depending upon the final clinical performance.Main outcome measure: Adverse fetal, neonatal and maternal outcome.Result: Based on the score cut off for the total leukocyte count was calculated to prognosticate the outcome. Leukocyte count of 15,850/mm 3 , at the time of admission was found to be able to predict the clinical outcome with a sensitivity of 85.7% and specificity of 87.6%, in a case of PPROM. Whereas the individual components of differential leukocyte counts were found to be not of much help in this regard.
Conclusion:Leukocyte count of 15,850/mm 3 at admission can be used to prognosticate outcome in pregnancies complicated with PPROM.