Clinical significance of contact lens related changes of ocular surface tissue observed on optical coherence images

Jandl, Alexandra; Ruland, Thomas; Schwarz, David; Wolffsohn, James S.; Pult, Heiko; Bandlitz, Stefan

doi:10.1016/j.clae.2020.11.008

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…Silicone hydrogel (SH) SCLs can interact with and modify biochemical tear film properties [ 3 ]. Prolonged and inappropriate use of these SH-SCLs could influence the ocular surface [ 4 ] and be associated with inflammatory variations [ 5 ], such as limbal and ciliary conjunctival redness [ 6 ], lacrimal morphology changes [ 7 ] or ocular surface disorders [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Celligent® Biomimetic Water Gradient Contact Lens Effects on Ocular Surface and Subjective Symptoms

et al. 2023

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This study aimed to evaluate the non-invasive and subjective symptoms associated with Lehfilcon A water gradient silicone hydrogel contact lenses with bacterial and lipid resistance technology. A prospective, longitudinal, single-centre, self-controlled study was conducted among silicone hydrogel contact lens wearers. Non-invasive analysis of the pre-lens tear film was performed using the Integrated Clinical Platform (ICP) Ocular Surface Analyzer (OSA), and the meibomian glands were evaluated with the Cobra® HD infrared meibographer. After 30 days of contact lens wear, the subjects were re-evaluated to determine the changes in conjunctival redness, subjective dry eye disease, tear meniscus height, lipid pattern, and non-invasive break-up time. Results showed that the lipid layer thickness decreased significantly from 2.05 ± 1.53 to 0.92 ± 1.09 Guillon patterns, and the tear meniscus height decreased from 0.21 ± 0.04 to 0.14 ± 0.03. The mean pre-lens non-invasive break-up time (NIBUT) significantly increased from 15.19 ± 9.54 to 25.31 ± 15.81 s. The standard Patient Evaluation of Eye Disease (SPEED) score also decreased from 7.39 ± 4.39 to 5.53 ± 4.83. The results suggest that Lehfilcon A significantly reduced lipid and aqueous tear film volume but improved break-up time and subjective dry eye symptoms.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Celligent® Biomimetic Water Gradient Contact Lens Effects on Ocular Surface and Subjective Symptoms

et al. 2023

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“…Advances in instrumentation have allowed us to better understand how soft contact lenses drape over the cornea and sclera (which is more of a tangent than previously thought), 193–197 the shape profile of contact lenses, 198 and the impact of lens design on its centration and mobility 173,199,200 . We developed a technique to compensate for image distortion due to the optics of the eye, 201 which had previously been overlooked, leading to the incorrect observation 202 that soft contact lenses significantly indent (embed into) the corneal epithelium 199,203 …”

Section: Impact Of Technological Advances In the Optics And Propertie...mentioning

confidence: 99%

“…175,192 Advances in instrumentation have allowed us to better understand how soft contact lenses drape over the cornea and sclera (which is more of a tangent than previously thought), [193][194][195][196][197] the shape profile of contact lenses, 198 and the impact of lens design on its centration and mobility. 173,199,200 We developed a technique to compensate for image distortion due to the optics of the eye, 201 which had previously been overlooked, leading to the incorrect observation 202 that soft contact lenses significantly indent (embed into) the corneal epithelium. 199,203 For contact lens wearers, we have shown that toric surfaces can improve the visual function of astigmats, [204][205][206][207][208] and multifocal optics can assist in ameliorating presbyopia, 50,183,209 although it is challenging to predict the benefits of different designs for an individual patient, as we and others have shown.…”

Section: Impact Of Technological Advances In the Optics And Propertie...mentioning

confidence: 99%

2022 Glenn A. Fry Award lecture: Enhancing clinical assessment for improved ophthalmic management

Wolffsohn

2024

Optom Vis Sci

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Detailed clinical assessment is critical to allow sensitive evaluation of the eye and its management. As technology advances, these assessment techniques can be adapted and refined to improve the detection of pathological changes of ocular tissue and their impact on visual function. Enhancements in optical medical devices including spectacle, contact, and intraocular lenses have allowed for a better understanding of the mechanism and amelioration of presbyopia and myopia control. Advancements in imaging technology have enabled improved quantification of the tear film and ocular surface, informing diagnosis and treatment strategies. Miniaturized electronics, large processing power, and in-built sensors in smartphones and tablets capacitate more portable assessment tools for clinicians, facilitate self-monitoring and treatment compliance, and aid communication with patients. This article gives an overview of how technology has been used in many areas of eye care to improve assessments and treatment and provides a snapshot of some of my studies validating and using technology to inform better evidence-based patient management.

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Rigid Scleral and Corneoscleral Lens Design and Fitting

Vincent¹

2024

Contact Lens Practice

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Clinical significance of contact lens related changes of ocular surface tissue observed on optical coherence images

Cited by 4 publications

References 23 publications

Evaluation of Celligent® Biomimetic Water Gradient Contact Lens Effects on Ocular Surface and Subjective Symptoms

Evaluation of Celligent® Biomimetic Water Gradient Contact Lens Effects on Ocular Surface and Subjective Symptoms

2022 Glenn A. Fry Award lecture: Enhancing clinical assessment for improved ophthalmic management

Rigid Scleral and Corneoscleral Lens Design and Fitting

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