Clinical significance of early‐diastolic tissue velocity imaging of lateral mitral annulus for prognosis of nonischemic left ventricular dysfunction

Abstract

Purpose We explored the potential of tissue velocity imaging (TVI) for prognosis of nonischemic left ventricular (LV) dysfunction (LVD). Methods We reviewed 138 nonischemic LVD patients (58 ± 14 years) who underwent both cardiac magnetic resonance (CMR) and echocardiography. Septal and lateral mitral annular TVI data were compared with late gadolinium enhancement (LGE) on CMR. During a mean follow‐up of 24 months, recovery (>15%) of LV ejection fraction and clinical outcomes (cardiovascular death and heart failure hospitalization) were assessed. Results LGE was commonly observed in the basal anteroseptal, inferoseptal, and inferior segments, but infrequently observed in the anterolateral segment. LGE was associated with lower early diastolic, septal (Sep‐e′ = 5.2 ± 2.0 vs 6.9 ± 2.0 cm/s, P = .031) and lateral (Lat‐e′ = 7.3 ± 3.0 vs 9.5 ± 2.0 cm/s, P < .001) TVI. The relationship between Lat‐e′ and anterolateral LGE (area under the curve, AUC 0.834) was much better than that between Sep‐e′ and inferoseptal LGE (AUC 0.699). The 60 patients with LVD reversibility revealed higher Lat‐e′ (9.8 ± 2.0 vs 6.7 ± 2.2 cm/s, P < .001) and lower LGE burden (7.3 ± 9.0 vs 22 ± 10%, P < .001), while Lat‐e′ ≤ 7.8 cm/s appeared unfavorable for 31 events patients. On multivariate analyses, Lat‐e′ (HR 0.79, 95% CI 0.63‐0.99, P = .044) and LVD reversibility (HR 0.53, 95% CI 0.16‐0.90, P = .018) were still meaningful together with LGE segments and burden. Conclusion Lat‐e′ was related with LVD reversibility and a significant predictor of clinical outcomes.

Classification and Recognition of Doppler Ultrasound Images of Patients with Atrial Fibrillation under Machine Learning

“…erefore, the difference between normal and abnormal is magnified, and the dependence on local changes is less. e average velocity of the various parts of the mitral valve ring in the early diastole can be used as a sensitive indicator to reflect the left ventricular diastolic function, and it will hardly be disturbed by heart rate and load [25,26]. e results of this study showed that the combined use of the TNN model can more accurately identify the Em, especially the E/Em value of patients with atrial fibrillation, which was greatly different from the control group, indicating that the left ventricular diastolic function measured by this method was more accurate.…”

Short Term Use of Empagliflozin Does Not Improve Left Ventricular Function in Non-Diabetic Hypertensive Patients: Results from a Non-Randomised Controlled Trial

“…Left ventricular filling pressure has proven to be an early marker and predictor of outcomes in cardiovascular diseases assessment and a number of echocardiographic measurements are used to estimate left ventricular pressure parameters [10]. The early lateral annular velocity (E'), the mitral profile (E/A) and the mitral annular early diastolic velocity (E/E') are commonly used for the evaluation of diastolic function by way of non-invasive echocardiographic assessment [11].…”