Clinical Significance of Late Gadolinium Enhancement on Cardiac Magnetic Resonance in Patients With Hypertrophic Cardiomyopathy

The Prognostic Implications of Cardiovascular Magnetic Resonance

“…LGE representing focal fibrosis is present in up to 80% of patients, 51 and LGE extent correlates with risk factors for sudden death and presence of heart failure and is predictive of nonsustained VT and atrial fibrillation. [52][53][54][55] Rubinshtein et al 56 (nϭ424; follow-up, 34 months) showed the absence of LGE conferred an excellent prognosis (no events versus 4.6% in those with LGE, PϽ0.002).…”

Distinguishing focal fibrotic lesions and non-fibrotic lesions in hypertrophic cardiomyopathy by assessment of regional myocardial strain using two-dimensional speckle tracking echocardiography: Comparison with multislice CT

“…Several studies have demonstrated that the extent of DHE has been associated with International Journal of Cardiology 158 (2012) 423-432 severity of myocardial damage and predictive markers of the occurrence of SCD in HCM subjects [13,[17][18][19][20]. Multislice computed tomography (MSCT), as well as MRI, has also been regarded as an independent useful tool for detection of focal fibrotic lesions in LVM [21] and estimation of prognosis of HCM.…”

Detection of Myocardial Fibrosis in Systemic Sclerosis by Contrast-Enhanced Magnetic Resonance Imaging

“…Coronary artery disease as a common cause of LGE seems to be very unlikely due to the observed non-ischemic pattern of LGE, and a very low likelihood (< 4%) of CAD in our LGE positive patients according to the SCORE criteria [33]. Left ventricular hypertrophy as another well known reason for patchy left ventricular LGE [34] can be excluded, because none of the LGE positive individuals exhibited left ventricular hypertrophy.…”