Clinical significance of lifetime mood and panic-agoraphobic spectrum symptoms on quality of life of patients with rheumatoid arthritis

Piccinni, Armando; Maser, Jack D.; Bazzichi, Laura; Rucci, Paola; Vivarelli, Laura; Debbio, Alessandro Del; Catena, Mario; Bombardieri, Stefano; Dell’Osso, L.

doi:10.1016/j.comppsych.2005.08.002

Cited by 28 publications

(19 citation statements)

References 39 publications

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“…Similar, worsening of QOL in the presence of psychiatric comorbidity has been seen in patients with other chronic inflammatory diseases such as rheumatoid arthritis[21] and chronic noninflammatory diseases such as type 2 diabetes. [22] QOL improves significantly with adequate intervention to address psychological distress.…”

Section: Discussionmentioning

confidence: 60%

Domains and Determinants of Quality of Life in Schizophrenia and Systemic Lupus Erythematosus

Radhakrishnan

Menon

Kanigere

et al. 2012

Indian Journal of Psychological Medicine

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Background:The World Health Organization Quality of Life-Bref (WHOQOL-Bref) scale was designed to measure quality of life (QOL) in both medical and psychiatric illnesses. There have been a few studies to date that compare aspects of QOL in medical and psychiatric illnesses.Aim:The aim of the study was to compare QOL in patients with systemic lupus erythematosus (SLE), a chronic medical illness and schizophrenia, a chronic psychiatric disorder.Materials and Methods:In a prospective design, 50 patients with SLE and 50 patients with schizophrenia were assessed on measures of QOL by using the WHOQOL-Bref scale, demographic factors, disease severity, and psychiatric comorbidity.Results:There was a significant difference between the SLE group and the schizophrenia group on the social domain of the WHOQOL-Bref scale but not on other domains. Patients with SLE had lower scores, except on social domain. Disease severity correlated with scores on the physical domain and environmental domain in both illnesses. The presence of psychiatric comorbidity was associated with significantly lower QOL scores in SLE. The presence of insight was associated with nonsignificantly lower QOL scores in schizophrenia. There was a significant association between QOL scores and both income and religious belief system in SLE, while age and duration of illness correlated with QOL scores in schizophrenia.Conclusion:Although the QOLs in schizophrenia and SLE were comparable on all domains except the social domain, the factors that mediate QOL in both these illnesses are different.

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Section: Discussionmentioning

confidence: 60%

Domains and Determinants of Quality of Life in Schizophrenia and Systemic Lupus Erythematosus

Radhakrishnan

Menon

Kanigere

et al. 2012

Indian Journal of Psychological Medicine

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“…Bazzichi et al reported that lifetime mood depressive symptoms, as assessed by the Mood Spectrum Questionnaire, Self-Report version (MOODS-SR), correlated with impairment of HRQOL in RA patients without a past psychiatric history [26]. According to the results of another study from this group, a significant worsening of all MOS SF-36 (Medical Outcomes Study 36-Item Short-Form Health Survey questionnaire) scores was related to higher scores for the depressive domains of MOODS-SR [27]. Rupp et al [28], in their study on 882 RA patients, reported that the assessment of somatic and psychological comorbidity through periodic screening needs to be included in the clinical management of RA in order to prevent poor outcomes.…”

Section: Discussionmentioning

confidence: 98%

Logistic regression models for predicting physical and mental health-related quality of life in rheumatoid arthritis patients

et al. 2008

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The aim of this work was to develop two logistic regression models capable of predicting physical and mental health related quality of life (HRQOL) among rheumatoid arthritis (RA) patients. In this cross-sectional study which was conducted during 2006 in the outpatient rheumatology clinic of our university hospital, Short Form 36 (SF-36) was used for HRQOL measurements in 411 RA patients. A cutoff point to define poor versus good HRQOL was calculated using the first quartiles of SF-36 physical and mental component scores (33.4 and 36.8, respectively). Two distinct logistic regression models were used to derive predictive variables including demographic, clinical, and psychological factors. The sensitivity, specificity, and accuracy of each model were calculated. Poor physical HRQOL was positively associated with pain score, disease duration, monthly family income below 300 US$, comorbidity, patient global assessment of disease activity or PGA, and depression (odds ratios: 1.1; 1.004; 15.5; 1.1; 1.02; 2.08, respectively). The variables that entered into the poor mental HRQOL prediction model were monthly family income below 300 US$, comorbidity, PGA, and bodily pain (odds ratios: 6.7; 1.1; 1.01; 1.01, respectively). Optimal sensitivity and specificity were achieved at a cutoff point of 0.39 for the estimated probability of poor physical HRQOL and 0.18 for mental HRQOL. Sensitivity, specificity, and accuracy of the physical and mental models were 73.8, 87, 83.7% and 90.38, 70.36, 75.43%, respectively. The results show that the suggested models can be used to predict poor physical and mental HRQOL separately among RA patients using simple variables with acceptable accuracy. These models can be of use in the clinical decision-making of RA patients and to recognize patients with poor physical or mental HRQOL in advance, for better management.

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“…10 Depression seems to decrease patients’ adherence to medical treatment 11 and is associated with increased disability, 4, 12 impaired quality of life, 13, 14 and reduced rates of clinically significant remission of RA symptoms and treatment response. 15–17 Patients with moderate or severe depression are less likely than those with mild or no depression to adhere to medical recommendations across a variety of medical conditions, 11 including RA.…”

Section: Psychiatric Comorbiditiesmentioning

confidence: 99%

Affective disturbance in rheumatoid arthritis: psychological and disease-related pathways

2016

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In addition to recurrent pain, fatigue, and increased rates of physical disability, individuals with rheumatoid arthritis (RA) show an increased prevalence of some mental health disorders, particularly those involving mood disturbances. This narrative Review provides an overview of mental health comorbidities in RA, and discusses how these comorbidities interact with disease processes, including dysregulation of inflammatory responses, prolonged difficulties with pain and fatigue, and the development of cognitive and behavioural responses that could exacerbate the physical and psychological difficulties associated with RA. This article describes how the social context of individuals with RA affects both their coping strategies and psychological responses to the disease, and can also impair responses to treatment through disruption of therapeutic alliance and treatment adherence. Evidence from the literature on chronic pain suggests that the resulting alterations in neural pathways of reward processing could yield new insights into the connections between disease processes in RA and psychological distress. Finally, the role of psychological interventions in the effective and comprehensive treatment of RA is discussed.

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Clinical significance of lifetime mood and panic-agoraphobic spectrum symptoms on quality of life of patients with rheumatoid arthritis

Cited by 28 publications

References 39 publications

Domains and Determinants of Quality of Life in Schizophrenia and Systemic Lupus Erythematosus

Domains and Determinants of Quality of Life in Schizophrenia and Systemic Lupus Erythematosus

Logistic regression models for predicting physical and mental health-related quality of life in rheumatoid arthritis patients

Affective disturbance in rheumatoid arthritis: psychological and disease-related pathways

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