Clinical Significance of Preoperative Virtual Colonoscopy for Evaluation of the Proximal Colon in Patient With Obstructive Colorectal Cancer

Abstract

PurposeVirtual colonoscopy is the most recently developed tool for detecting colorectal cancers and polyps, but its effectiveness is limited. In our study, we compared the result of preoperative virtual colonoscopy to result of preoperative and postoperative colonoscopy. We evaluated also the accuracy of preoperative virtual colonoscopy in patients who had obstructive colorectal cancer that did not allow passage of a colonoscope.MethodsA total of 164 patients who had undergone preoperative virtual colonoscopy and curative surgery after the diagnosis of a colorectal adenocarcinoma between November 2008 and August 2013 were pooled. We compared the result of conventional colonoscopy with that of virtual colonoscopy in the nonobstructive group and the results of preoperative virtual colonoscopy with that of postoperative colonoscopy performed at 6 months after surgery in the obstructive group.ResultsOf the 164 patients, 108 were male and 56 were female patients. The mean age was 62.7 years. The average sensitivity, specificity, and accuracy of virtual colonoscopy for all patients were 31.0%, 67.2%, and 43.8%, respectively. In the nonobstructive group, the average sensitivity, specificity, and accuracy were 36.6%, 66.2%, and 48.0%, respectively, whereas in the obstructive group, they were 2%, 72.4%, and 25.4%. Synchronous cancer was detected via virtual colonoscopy in 4 of the 164 patients.ConclusionVirtual colonoscopy may not be an effective method for the detection of proximal colon polyps, but it can be helpful in determining the therapeutic plan when its results are correlated with the results of other studies.

Correlation between microsatellite instability and RAS gene mutation and stage Ⅲ colorectal cancer

“…At present, surgical resection is the main treatment of CRC (2). However, due to differences in genotypes among different individuals, the incidence of drug resistance during chemotherapy increases significantly (3). Therefore, how to achieve personalized treatment of CRC under the guidance of precision medical treatment has been the focus of treatment in recent years.…”

Application of Virtual Endoscopy in Microvascular Decompression of Trigeminal Neuralgia

“…Virtual endoscopy (VE) has emerged as a noninvasive imaging technology that uses computer processing of 3D image datasets (such as CT or MRI scans) to produce simulated visualizations of specific organs of patients similar or equivalent to those produced by standard endoscopic procedures, 6 and more importantly it allows for the visualization of the region of interest at any angle, locating the operation site, reconstructing the anatomical structure surrounding the region, assisting diagnosis and treatment, and simulating surgical procedure 7 . Thus, it has been widely used in ophthalmology, otorhinolaryngology, neurosurgery, radiology, and gastroenterology 8–11 . The main purpose of this study is to evaluate the accuracy of VE in MVD for the treatment of TN.…”

“…7 Thus, it has been widely used in ophthalmology, otorhinolaryngology, neurosurgery, radiology, and gastroenterology. [8][9][10][11] The main purpose of this study is to evaluate the accuracy of VE in MVD for the treatment of TN.…”