Clinical significance of the water retention and barrier function‐improving capabilities of ceramide‐containing formulations: A qualitative review

Kono, Toru; Kawashima, Makoto

doi:10.1111/1346-8138.16175

Cited by 18 publications

(11 citation statements)

References 57 publications

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“…In many studies, the skin barrier has been improved by the application of products that contain ceramide to dry skin; however, there are few studies that show its effect on healthy normal skin. 16 One hour after cream application, the sebum content of the skin increased significantly because of the lipid components present in the cream. However, there was no significant difference in sebum content between the cream-treated and nontreated sites after 6 h. This is because even the nontreated site can protect the skin barrier during daytime by secreting sebum with a content similar to that of the treated site.…”

Section: Discussionmentioning

confidence: 99%

Effects of winter indoor environment on the skin: Unveiling skin condition changes in Korea

Park¹,

Jo²,

Jeon³

et al. 2023

Skin Research and Technology

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Background: In Korea, winter can cause skin dryness due to low relative humidity (RH); moreover, indoor heating devices promote moisture loss and air pollution. If dryness persists, dead skin cells accumulate, leading to skin problems; therefore, careful skin care is required. This study aimed to compare changes in skin conditions when exposed to an indoor environment for a short period of 6 h in winter, and to suggest proper winter skin care practices. Methods:A randomized, split-face clinical study was conducted in which healthy female participants with normal skin were exposed to an indoor environment with a heater turned on for a short period at least 6 h per day in the winter season, and cream was applied to one side of the face. Skin temperature, hydration, sebum, transepidermal water loss (TEWL), elasticity, texture, pores, redness, and wrinkles were measured at the treated and nontreated sites. Results:After 6 h of exposure, skin temperature, pores, roughness, redness, and wrinkles significantly increased (p < 0.05) on the face, whereas TEWL significantly increased on the forearm (p < 0.05). However, sebum secretion appeared to function as a barrier to maintain homeostasis in the facial skin. Elasticity, pores, texture, and wrinkles in the cream-treated ceramide site improved compared to those in the nontreated site (p < 0.05). The moisture content was also significantly higher in the forearm (p < 0.05). Conclusion:Changes in skin parameters of participants with healthy skin were observed even after short-term exposure to an indoor environment in winter. Creams containing ceramide maintain skin homeostasis and protect the skin barrier; therefore, it is recommended to use such creams to prevent skin damage and maintain healthy skin, particularly during prolonged exposure to indoor environments during winter.

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Section: Discussionmentioning

confidence: 99%

Effects of winter indoor environment on the skin: Unveiling skin condition changes in Korea

Park¹,

Jo²,

Jeon³

et al. 2023

Skin Research and Technology

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“…It is well known that a reduction of ceramide content in SC (stratum corneum) can lead to barrier disruption and dry skin. Topical ceramide-containing preparations can improve barrier function and dry skin in patients with atopic dermatitis [ 217 ]. The synthesis of endogenous ceramide is the first step in barrier recovery.…”

Section: Natural Products As Moisturizersmentioning

confidence: 99%

Natural products in cosmetics

Liu

2022

Nat. Prod. Bioprospect.

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The global cosmetics market reached US$500 billion in 2017 and is expected to exceed US$800 billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as one of the fastest-growing industries of the past decade. Data shows that the Chinese cosmetics market was US$60 billion in 2021. It is expected to be the world's number one consumer cosmetics market by 2050, with a size of approximately US$450 billion. The influence of social media and the internet has raised awareness of the risks associated with the usage of many chemicals in cosmetics and the health benefits of natural products derived from plants and other natural resources. As a result, the cosmetic industry is now paying more attention to natural products. The present review focus on the possible applications of natural products from various biological sources in skin care cosmetics, including topical care products, fragrances, moisturizers, UV protective, and anti-wrinkle products. In addition, the mechanisms of targets for evaluation of active ingredients in cosmetics and the possible benefits of these bioactive compounds in rejuvenation and health, and their potential role in cosmetics are also discussed.

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“…This matrix, which consists of ceramides, cholesterol, and free fatty acids, maintains skin hydration by preventing water loss from the epidermis, but in the elderly there is a decrease in ceramide levels in the SC, resulting in changes in these functions. In addition, the matrix also plays a role in regulating skin moisture, maintaining a strong bond between corneocytes, and regenerating cells (Kono et al, 2021;Stull & Yosipovitch, 2015). Corneocytes contain natural moisturizing factors, which are a collection of hygroscopic compounds, which attract and retain water within the cells.…”

Section: Reducing Skin Hydration Levels In the Elderlymentioning

confidence: 99%

The Role of Essential Oils on Improving Elderly Skin Hydration

Wijayadi¹,

Kelvin²

2022

midwifery

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Skin hydration has an important role in various diseases of the elderly. Skin hydration is determined by two factors, namely the ability of the stratum corneum (SC) to retain water due to natural moisturizing factors and the barrier function of the intercellular lipid lamellar structure and tight junctions. Several parameters are usually used for skin hydration, such as surface water content (SWC) and trans-epidermal water loss (TEWL). With age, several changes in the skin affect hydration, including changes in the cellular and intercellular lipid matrix, skin pH, SC protease enzymes, decreased sebaceous and sweat gland activity, and decreased estrogen levels in women. Therefore, a moisturizer is needed to minimize the unwanted effects of some of these changes. Selection of the type of moisturizer is very important for the elderly, especially moisturizers with antiseptic, antibacterial, and antioxidant effects are highly recommended. The ability of essential oils as components of moisturizers has been proven in various studies. Essential oils can improve the function of the epidermal barrier and help prevent transepidermal water loss. Therefore, this literature review discusses the role of various essential oils, namely green tea oils (Camellia sinensis or Camellia assamica), virgin coconut oils (Cocos nucifera L.), evening primrose oils (Oenothera paradoxa), grape seed oils (Vitis vinifera L.) .), rosemary oils (Rosmarinus officinalis L.), immortelle oils (Helichrysum italicum), and cannabis seeds oils (Cannabis sativa L.) on improving skin hydration in the elderly.

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Clinical significance of the water retention and barrier function‐improving capabilities of ceramide‐containing formulations: A qualitative review

Cited by 18 publications

References 57 publications

Effects of winter indoor environment on the skin: Unveiling skin condition changes in Korea

Effects of winter indoor environment on the skin: Unveiling skin condition changes in Korea

Natural products in cosmetics

The Role of Essential Oils on Improving Elderly Skin Hydration

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