Clinical significance of thickened sphenoid sinus mucosa in rathke's cleft cyst

Takasuna, Hiroshi; Sase, Taigen; Ito, Hidemichi; Ono, Hajime; Oshio, Kotaro; Tanaka, Yuichiro

doi:10.4103/sni.sni_283_17

Cited by 4 publications

(7 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some of these studies suggest that NFPA may lead to mucosal thickening in the SS. [5][6][7] Takasuna et al 9 retrospectively reviewed 84 patients with pituitary lesions, which included 51 PA, 18 Rathke's cleft cyst and 15 other tumours. The frequency of SS mucosal thickening was 16.7% and 2% for Rathke's cleft cyst and PAs, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Only a few studies noted that SS mucosal thickening can be detected on preoperative MRI scans in patients with pituitary apoplexy (PA) and Rathke's cleft cyst. [5][6][7][8][9] However, the reported incidences in these studies were different from each other, and some of them had a relatively small sample size. On the other hand, there is no study that has investigated the relationship between NFPAs and SS mucosal thickening.…”

mentioning

confidence: 91%

See 1 more Smart Citation

Sphenoid sinus mucosal thickening in patients with non‐functioning pituitary adenoma

Şahin

Topaloğlu

2021

Int J Clin Pract

View full text Add to dashboard Cite

Non-functioning pituitary adenomas (NFPAs), or as recently suggested, "non-functioning pituitary neuroendocrine tumors," are benign hypophyseal neoplasms that originate from adenohypophyseal cells. 1 NFPAs are not related to clinical or biochemical evidence of hormonal excess. 1,2 The lack of clinical symptoms of hormonal hypersecretion generally causes a delay in diagnosis. Therefore, NFPAs are commonly diagnosed when they are large enough to have mass effects on surrounding neurovascular structures. 1 The sphenoid sinus (SS) has a great importance as the gateway to the pituitary fossa during transnasal transsphenoidal surgery. It varies in size and shape and is located in the centre of the skull base. Various sinus and non-sinus diseases may affect the SS and can manifest in ways such as mucosal thickening, fluid collection, and partial or total opacification on radiologic imaging modalities.Isolated SS pathologies are relatively rare, and among patients with rhinosinusitis, isolated sphenoiditis incidence was reported as 1% to 3%. 3 Moreover, in a population-based study conducted on healthy individuals aged 50-65 years, SS mucosal thickening was detected in only 136 of 1963 sinuses (7%) on magnetic resonance imaging (MRI) scans. 4

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 91%

Sphenoid sinus mucosal thickening in patients with non‐functioning pituitary adenoma

Şahin

Topaloğlu

2021

Int J Clin Pract

View full text Add to dashboard Cite

show abstract

“…Inconsistencies in the incidence of SS mucosal thickening on preoperative MRI scans among patients diagnosed with pituitary apoplexy and Rathke's cleft cyst have been reported [7][8][9][10][11]. Only Şahin B et al explored the association between the presence of NFPA and SS mucosal thickening [5].…”

Section: Discussionmentioning

confidence: 99%

“…In a recent study of healthy individuals aged 50 to 65 years, SS mucosal thickening was observed in only 7% of sinuses on MRI scans [6]. Discrepancies in the incidence of sphenoid sinus (SS) mucosal thickening on preoperative MRI scans among patients diagnosed with pituitary apoplexy (PA) and Rathke's cleft cyst have been reported [7][8][9][10][11]. In a recent paper, Şahin B et al assessed the relationship between NFPAs and SS parameters (mucosal thickening, cysts, lateral recess, distances between carotid arteries and optic nerves) on MRI scans [5].…”

Section: Introductionmentioning

confidence: 99%

Magnetic Resonance Imaging Features of the Sphenoid Sinus in Patients with Non-Functioning Pituitary Adenoma

Ciurea,

Florian,

Lenghel

et al. 2024

Medicina

View full text Add to dashboard Cite

Background and Objectives: A magnetic resonance imaging (MRI) scan is part of the diagnostic protocol in pituitary adenoma patients. The goal of the present study is to present and analyse the MRI appearances of the sphenoid sinus (SS) in patients with non-functioning pituitary adenoma (NFPA). Materials and Methods: This is a retrospective case–control study conducted between January 2015 and December 2023 in a tertiary referral hospital. Forty NFPA patients were included in the study group, while the control group consisted of 30 age- and gender-matched cases. Results: The sellar type of SS pneumatization was the most frequently encountered pattern among both groups. The presence of the lateral recess of the SS, mucosal cysts, and sphenoethmoidal cells was similar in both patient groups. The proportion of patients with SS mucosal thickness greater than 3 mm was 42.5% in NFPA group and 3% in the control group, and this difference was statistically significant (p < 0.001). The space between the two optic nerves was significantly larger in the NFPA group as compared to the control group (p < 0.001). Conclusions: Our study was able to establish a statistically significant association between the presence of NFPA and both the thickening of the SS mucosa and increased space between optic nerves.

show abstract

“…For instance, SS pathology may manifest radiologically as membrane thickening in conditions such as isolated sphenoid sinusitis, pituitary apoplexy, and anterior/posterior pituitary dysfunction (Arita et al 2001). This membrane thickening can be the result of a sudden increase in intrasellar pressure which causes congestion of dural blood flow, thus leading to membrane thickening (Takasuna et al 2017). In the present study, although, the frequency of pathological findings (18.2%) such as membrane bulging or complete sinus opacification was much less compared to the percentage of healthy sinuses (81.8%), their timely diagnosis is paramount.…”

Section: Discussionmentioning

confidence: 99%

Morphometric characteristics of the sphenoid sinus and potential influencing factors: a retrospective assessment using cone beam computed tomography (CBCT)

et al. 2021

View full text Add to dashboard Cite

The present study aimed to evaluate the morphological characteristics of the sphenoid sinus (SS), and the impact of potential influencing factors on the morphometric features using CBCT imaging. CBCT scans of 148 patients, aged between 15 and 85 (32.88 ± 15.33) years were retrospectively evaluated. DICOM files from the CBCT scans were imported into semi-automatic software and the SS of each patient was assessed for the morphological characteristics including configuration, symmetry, extension, shape, septation, volume, and maximum diameter. Furthermore, potential influencing factors such as age, gender, side, and sinus condition were analysed. A significant association was observed between sinus extension and age. Septation was also found to be significantly associated with age, gender and sinus condition. Besides, sinus volume was significantly associated with gender and sinus condition. No significant influence of shape and side on the morphometric features was noticed. The average volume and diameter of the SS were 6576.92 ± 3748.12 mm3 and 30.48 ± 9.28 mm, respectively. In conclusion, the present findings indicate that age, gender and sinus condition have a significant impact on the morphometric characteristics of the SS. Mature sinuses exhibit a post-sellar extension pattern until middle age. In addition, males, and sinuses with healthy sinus condition have larger volumes compared to females and pathological sinuses.

show abstract

Clinical significance of thickened sphenoid sinus mucosa in rathke's cleft cyst

Cited by 4 publications

References 13 publications

Sphenoid sinus mucosal thickening in patients with non‐functioning pituitary adenoma

Sphenoid sinus mucosal thickening in patients with non‐functioning pituitary adenoma

Magnetic Resonance Imaging Features of the Sphenoid Sinus in Patients with Non-Functioning Pituitary Adenoma

Morphometric characteristics of the sphenoid sinus and potential influencing factors: a retrospective assessment using cone beam computed tomography (CBCT)

Contact Info

Product

Resources

About