Clinical spectrum of splenic infarction – a South Indian perspective

Vijayaraghavan, Srinivasan; Thomas, Jerrin

doi:10.3823/1997

Cited by 3 publications

(2 citation statements)

References 9 publications

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“… 3 In another study, there were 25 cases of SI among 168,572 admissions over a two-year period, corresponding to a quite similar prevalence of 0.015%. 7 Among patients with COVID-19, the estimated prevalence of SI appears to be higher than that.…”

Section: Discussionmentioning

confidence: 96%

Splenic Infarction with Aortic Thrombosis in COVID-19

Sztajnbok

Brasil

Romero

et al. 2021

The American Journal of the Medical Sciences

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Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19.

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Section: Discussionmentioning

confidence: 96%

Splenic Infarction with Aortic Thrombosis in COVID-19

Sztajnbok

Brasil

Romero

et al. 2021

The American Journal of the Medical Sciences

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“…Splenic infarction may lead to severe consequences if missed on initial emergent exam. Currently, there are limited studies available that attempt to identify the prevalence, etiologies, interventions, and outcomes of splenic infarction in the pediatric population [8]. A massive splenic infarction is described as parenchymal ischemia secondary to vessel occlusion leading to tissue necrosis of at least half of the spleen [9].…”

Section: Discussionmentioning

confidence: 99%

Rare Cause of Abdominal Pain in an Adolescent Patient: Splenic Infarction in Absence of Causative Underlying Hematologic Disorder

Shimshoni¹,

Vandillen²

2020

Cureus

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Splenic infarction is a rare medical condition that usually occurs in the setting of hematologic disorders. It is rarely seen in previously healthy adolescents. A wandering spleen increases the risk of splenic infarct due to risk of torsion and is more commonly seen in pregnancy due to increased elasticity of connective tissue. Wandering spleen may also be associated with diseases, such as Ehlers-Danlos, and should be suspected in the patient with possible underlying connective tissue dysfunction. Although rare, splenic infarction must be on the differential for unremitting upper epigastric pain, fever, and vomiting, particularly when patient medical history suggests connective tissue dysfunction. This case discusses the course of a pediatric patient with abdominal pain with complex medical history found to have splenic infarction secondary to torsion of a wandering spleen initially discovered on emergency CT imaging. Although rarely indicated in pediatric patients with abdominal pain, lower threshold for CT imaging for ruling out emergent etiology resulted in life-saving treatment. This case demonstrates the importance of clinical suspicion for emergency etiology of abdominal pain in pediatric patients with medical history suspicious for connective tissue dysfunction, and therefore lowering the threshold for CT imaging to rule out splenic infarction in these patients.

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