Clinical Studies and Operative Methods of Gastric Cancer in Patients Over 80 Years Old

Shimomatsuya, Takumi; Horiuchi, Tetsuya; Yoshida, Makoto; Amaya, Hirokazu; Aotake, Toshiharu; Uchinami, Masaru; Muraoka, Ryusuke

doi:10.3919/jjsa.60.2305

Cited by 2 publications

(3 citation statements)

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“…This may be due to the fact that postoperative complications were avoided through minimally invasive surgery, or because reduced surgery was chosen in order to ensure a good prognosis for the comorbidities. Some studies have suggested that diseases other than cancer may account for a high percentage of deaths in elderly patients with gastric cancer [8,12,13]. In this study, 11 patients (19.6%) in Group A and 22 (13.7%) in Group B died due to diseases other than cancer.…”

Section: Discussionmentioning

confidence: 57%

“…Thus, we have investigated the clinicopathological features, surgical procedures, complications, and prognosis in elderly patients, especially patients aged 85 and above, who underwent gastric resection for gastric cancer. Many elderly patients experience preoperative complications [8], and therefore it is important to as- sess major organs and physiological age in order to determine whether or not gastric cancer surgery can be performed on such patients. This is often difficult due to increased individual differences among patients of advanced age that cannot be determined by chronological age alone.…”

Section: Discussionmentioning

confidence: 99%

“…The first type of studies recommended that prognosis was mainly affected by the degree of cancer progression, irrespective of age, and therefore that prognosis could be improved by successful conservative surgery, good perioperative care, and aggressive general treatment [13]. The second type recommended minimally invasive surgery due to the prevalence of preoperative comorbidity and reduced major organ functions in the elderly, as well as their high rate of postoperative complications and high number of deaths due to other diseases [8,12]. Our investigation revealed that the factors that negatively affected prognosis included undifferentiated cancer, advanced cancer stage, degree of lymph node dissection, degree of residual tumor, total gastrectomy, and hemorrhage.…”

Section: Discussionmentioning

confidence: 99%

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Surgical Procedures, Complications, and Prognosis for Gastric Cancer in the Very Elderly (^|^gt;85): A Retrospective Study

et al. 2012

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Summary: Many elderly individuals suffer from reduced functioning of major organs with cardiovascular and respiratory system comorbidity. Consequently, surgical stress and postoperative complications can be fatal. We investigated whether gastrectomy can safely improve the prognosis in very elderly (>85 years) patients with gastric cancer. We compared the clinical and pathological features of patients 85 years and older (Group A) with those 80-to 84-year-old (Group B) who underwent gastrectomy. We also compared the survival rates of Group A and Group B, and investigated the prognostic factors. Group A had a high incidence of patients with 3 or more comorbidities, but these did not influence postoperative complications or survival rate. Patients at stage I or II had a significantly higher survival rate than those who did not undergo surgery. However, there was no statistical difference in survival rate at stage III or IV. Our study results revealed that in the early stages (I and II) of welldifferentiated gastric cancer with low risk of lymph node metastasis, surgery should consist of minimal lymphadenectomy and be minimally invasive. Further, treatments other than gastrectomy should be considered for patients in whom complete resection via reduction surgery is not possible. Key words

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Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%