Clinical Study of Coma in Children

Chelliah, Luke Ravi

doi:10.18535/jmscr/v5i8.12

Cited by 1 publication

(2 citation statements)

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“…The organophosphate poisoning in children less than 5 years is more likely explained by accidental ingestion. Overall mortality in our study was 18.2%, which is comparable to studies done by Forsberg et al, 6 Chelliah et al, 28 and Khodapanahandeh and Najarkalayee, 29 who reported 35%, 8.6%, and 16.6% mortality rates, respectively. We detected the highest mortality from NTCs to be in children below 5 years of age.…”

Section: Discussionsupporting

confidence: 89%

“…Our study was also consistent with their finding that lower GCS score was accompanied with poor prognosis and higher mortality rate. 6,28 Furthermore, all of our patients who presented with a GCS less than 5 died. Owolabi et al 31 reported that patients with 3-5 GCS scores had a greater possibility of death and prolongation of coma than those with scores of 6-8.…”

Section: Discussionmentioning

confidence: 79%

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Clinico-Etiological Profile and Predictors of Mortality of Nontraumatic Coma in Children of Upper Egypt: A Prospective Observational Study

Baseer

Mohamad

Qubaisy

et al. 2022

The American Journal of Tropical Medicine and Hygiene

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Nontraumatic coma (NTC) is a considerable cause of morbidity and mortality in children. This prospective observational study aimed to determine the clinico-etiological profile of NTC in children and delineate clinical signs predicting mortality in Upper Egypt from June 2019 to May 2020. All children from 1 month of age to 16 years who were admitted with NTC were included in the study. All patients received full histories and physical examinations, including Glasgow Coma Scale (GCS). Routine laboratory investigations including complete blood count, electrolytes, blood sugar, serum creatinine, and liver function tests were performed for all patients. Specific investigations such as metabolic studies, lumbar punctures, brain computed tomography scans, and magnetic resonance imaging were done when indicated. The precise etiology was determined and clinical presentations for survivors and nonsurvivors were compared. Among the 137 cases of NTC identified, central nervous system (CNS) infections were the most common cause leading to 38 cases, followed by toxic causes in 37 cases, status epilepticus in 22 cases, and metabolic causes in 21 cases. Hypothermia, hypotension, abnormal respiratory patterns, muscle hypotonia, absent corneal reflex, presence of shock, and need for mechanical ventilation were significantly correlating with mortality. The estimated mortality rate was 18.2% and all cases with GCS < 5 died. Toxic causes were the most commonly identified etiology in patients who died. In conclusion, the authors identified several etiologies for NTC in Upper Egypt and their corresponding clinical signs at presentation. This information can be used to improve the clinical care provided to children with NTC.

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Section: Discussionsupporting

confidence: 89%