Clinical study of combined application of iRoot-BP and collagen sponge in apical barrier surgery

Abstract

This research aimed to observe the clinical effects of iRoot-BP along with collagen sponge applied in apical barrier surgery. 46 immature teeth were divided into traumatic group (n =25) and non-traumatic group (n =21) according to the etiology of necrotic pulps. While depending on whether collagen sponges are used during the apical barrier surgery, the 46 teeth were randomly divided into non-collagen group (n = 23) and collagen group (n = 23). Patients were scheduled for follow-up during 12 months to undergo clinical and radiological examination. The etiological analysis showed that the failure of both groups were caused by trauma, which indicated that there might be a negative correlation between trauma and success rate of periapical tissue healed (χ2 = 2.696, P = 0.10). Healing results of apical lesions indicated that 22 affected teeth in collagen group and 21 affected teeth in non-collagen healed well, without clinical and imaging manifestations of failure (χ2 = 0.357, P = 0.55). Assessment results of root sustainable growth suggested that the incomplete tooth roots in collagen group had different degrees of growth, with an average increase of about 2 mm (P <0.05). The combined application of iRoot-BP and collagen sponge in apical barrier surgery can promote immature roots formation, and make them more similar to normal roots formation.