Clinical Study of Demographic Profile, Etiology, Severity and Outcome of Acute Pancreatitis in a Tertiary Care Teaching Hospital in Northern India

Ahlawat, Vijay; Godara, Rajesh

doi:10.4172/2161-069x.1000575

Cited by 8 publications

(13 citation statements)

References 17 publications

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“…The acute fluid collection was identified in 26.6% of cases in the present study, which is consistent with the findings of Raghuwanshi et al in a study in Bhopal, where it was found in 34% of patients, and Banday et al in a study in Jammu, where it was found in 36%. 13,14 Similar results were observed in Ramu et al in 33.715% of cases, there was an acute fluid collection. 6 In the present study, the most prevalent systemic consequence was respiratory system involvement (15%).…”

Section: Discussionsupporting

confidence: 82%

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Retrospective analysis of etiological factors and clinical presentation of pancreatitis in patients of a tertiary care hospital

Mandalapu

2022

Int Surg J

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Background: Acute pancreatitis is a complicated illness with a wide range of local and systemic consequences that surgeons throughout the world deal with. This study evaluated the etiology and clinical presentation of acute pancreatitis patients retrospectively in a tertiary health care center.Methods: This study is a cross-sectional, retrospective hospital-based study that was conducted from Feb 2012 to Feb 2020 which was conducted on 500 patients who had acute pancreatitis in the department of general surgery and gastroenterology in a tertiary health care center.Results: Out of the total of 500 patients, 75% of males had acute pancreatitis and 25% of females had acute pancreatitis. The 52% of the patients had epigastric pain without radiating to the back and it was the most common clinical presentation followed by 30% of the patients had epigastric pain radiating to the back followed by generalized abdominal pain (18%). Nausea and vomiting were observed in most of the cases (71%). Alcohol-induced pancreatitis was the most common (41.2%) among the 500 cases, followed by idiopathic pancreatitis (36.2%). The acute fluid collection was identified in 26.6% of cases. The most prevalent systemic consequence was respiratory system involvement (15%).Conclusions: The most common clinical manifestation was epigastric pain with no radiation to the back. In our study, the incidence of alcoholic pancreatitis (41.2%) and idiopathic pancreatitis (36.2%) was slightly greater, prompting us to look for additional aetiologies in the idiopathic category in future investigations.

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Section: Discussionsupporting

confidence: 82%

“…In Ramu et al study, the severity of the disease was mild in 82.1% of cases and severe in 4.4%. 6 In research conducted by Ahlawat et al 14 in North India, where 82 percent of cases were classed as mild. Similar results were observed in Nesvaderani et al study.…”

Section: Discussionmentioning

confidence: 98%

Retrospective analysis of etiological factors and clinical presentation of pancreatitis in patients of a tertiary care hospital

Mandalapu

2022

Int Surg J

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“…Similar results were obtained in the study done in North India by Ahlawat et al where 82% cases were classified as mild. 14…”

Section: Discussionmentioning

confidence: 99%

Etiology, clinical profile and outcome of acute pancreatitis in a tertiary care teaching hospital in rural South India: a ten year retrospective study

et al. 2019

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Background: Acute pancreatitis is a complex condition with diverse local and systemic complications, dealt by the surgeons all over the world. There were no previous detailed studies regarding the etiology, clinical profile and outcome of acute pancreatitis in rural Kerala.Methods: This is a hospital based study by retrospective chart analysis of all acute pancreatitis cases from the past 10 years in this tertiary care centre which have clinical/ laboratory/ radiological findings suggestive of acute pancreatitis.Results: Among 436 cases studied 318 (72.9%) were males and 118 (27.1%) were females. Epigastric pain without radiation to the back (51.6%) was the most common clinical presentation. Alcohol was the most common etiological factor seen in 42.4% followed by idiopathic pancreatitis (IP) (36.9% cases) and then by gallstone/biliary pancreatitis (14.5%). Acute fluid collection was the most common local complication seen in 29.1% cases and respiratory system involvement was the most common organ involvement seen in 16.5% of cases.Conclusions: Epigastric pain without radiation to the back was the most common clinical presentation. Incidence of alcoholic pancreatitis (42.4%) and idiopathic pancreatitis (36.9%) was slightly higher in our study, which should prompt us to look with further studies for identifiable new aetiologies in the idiopathic group. This work provides the first known regional description of the etiology, clinical profile and outcome of acute pancreatitis. Due to institutional and population similarities, this may represent the status of developing countries in general. This will help in formulating a hospital policy which would be beneficial.

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“…The majority of patients were in the age group of 36-45 years with AP. Similarly, Ahlawat et al [9] found that the mean age of the study sample (n = 50) was 47.30 ± 15.16 (SD) years, ranging from 19 to 75 years. In a study by Das et al [10], 63% of patients were in the age group of 20-39 years, 28% in 40-59 years, 4% in <20 years, and 5% in 60-80 years.…”

Section: Discussionmentioning

confidence: 65%

Clinical, Biochemical, and Radiological Correlation in the Severity of Acute Pancreatitis: A Retrospective Study

Saxena¹,

Kumar²,

Nafe³

et al. 2023

Cureus

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Objectives: To analyze the etiologies and the varying clinical presentations and to validate the clinical, biochemical, and radiological signs with severity and prognosis of acute pancreatitis.Methods: A retrospective study of 1316 patients diagnosed with acute pancreatitis in an industrial hospital in Jamshedpur, Jharkhand, was conducted, and their clinicoradiological profiles, etiological factors, and outcomes were studied.Result: A total of 1316 cases were enrolled, out of which maximum cases (411 [31.23%]) were from the age group of 30-44 years, and the mean and median age were 44.54 and 47 years, respectively. A total of 731 (55.45%) patients had social habits (i.e., alcohol and smoking), and 585 (44.45%) patients did not have any social habits. Based on the etiology of acute pancreatitis (AP), the majority of cases were due to alcoholism (710 [53.95%]) followed by gallstone (343 [26.06%]) and idiopathic pancreatitis (217 [16.48%]). As per the severity of AP, most patients showed mild pancreatitis (937 [71.20%]) followed by moderate (312 [23.71%]) and severe pancreatitis (67 [05.09%]). Mild and moderate pancreatitis patients were shown in 85 and 28 cases, respectively, suggestive of chronic pancreatitis after repeated episodes of AP. But severe pancreatitis shown in 19 cases had hypocalcemia + shock + multi-organ dysfunction syndrome (MODS). In mild, moderate, and severe AP, the mortality rates were 19 (02.03%), 44 (14.10%), and 21 (31.34%), respectively. Overall, 1232 (93.62%) of AP cases recovered and were discharged in stable condition, but 84 (06.38%) cases expired.Conclusion: AP is a common cause of acute abdomen in patients presenting to the surgical emergency department. The management is mainly conservative with surgery limited to only a few selected cases, depending upon the severity of the disease.

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Clinical Study of Demographic Profile, Etiology, Severity and Outcome of Acute Pancreatitis in a Tertiary Care Teaching Hospital in Northern India

Cited by 8 publications

References 17 publications

Retrospective analysis of etiological factors and clinical presentation of pancreatitis in patients of a tertiary care hospital

Retrospective analysis of etiological factors and clinical presentation of pancreatitis in patients of a tertiary care hospital

Etiology, clinical profile and outcome of acute pancreatitis in a tertiary care teaching hospital in rural South India: a ten year retrospective study

Clinical, Biochemical, and Radiological Correlation in the Severity of Acute Pancreatitis: A Retrospective Study

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