Clinical study of metastatic tumors in the oral cavity.

Seino, Masataka; Ohbayashi, Takehisa; Migiyama, Hironiri; Maki, Masahiro; Yagi, Yoshiteru; Ohta, Kazutosi; Sakamoto, Mayumi; Nishikawa, Aya; Shunohara, Masanori

doi:10.5843/jsot.12.321

Cited by 4 publications

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“…Several studies have recommended palliative treatment (e.g., surgical treatment, chemotherapy, and radiotherapy) to improve the quality of life (QOL) and to maintain the patient's comfort 7,8 . We found 54 cases of oral metastasis of PCs that were reported from 1991 to 2021 in PubMed and Google scholar 9–45 and reviewed these cases, including our case. Kaplan‐Meier survival analyses were performed to determine whether palliative treatment affected overall survival.…”

Section: Discussionmentioning

confidence: 91%

“…In our review, 41 of 54 patients received palliative treatments, and surgical treatments were common ( n = 10), followed by chemoradiotherapy ( n = 8) (Table 1). 8–44 There were no significant differences in the survival times between patients with and without palliative treatment at 6.49 and 4.36 months, according to the results of the Kaplan‐Meier test (log rank test: P = 0.437, Figure 4), which suggested that palliative treatment had no effect on survival time. Our patient was able to consume food orally using the upper denture after surgical treatment, showing that even if radical therapy cannot be administered, palliative treatment for maintaining oral function may contribute to the improvement of the QOL.…”

Section: Discussionmentioning

confidence: 95%

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Metastasis of pulmonary adenocarcinoma to the oral cavity: A case report and literatures review of the last 30 years

Kawaharada

Maruyama

Abé

et al. 2022

Oral Science International

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Background: Metastases of pulmonary adenocarcinomas (pADCs) into the oral cavity are rare and sometimes misdiagnosed because of clinical findings that are similar to benign or inflammatory lesions.Case presentation: A 79-year-old man had a soft elastic mass in the oral cavity.Cytological and histological examinations revealed a metastasis of a pADC that was vimentin-positive. Conclusion:Oral cytology may be valuable for the detection of metastatic lesions in the oral cavity. Palliative surgery for maintaining the oral function may be beneficial to improve quality of life, and it did not affect survival time in Kaplan-Meier analysis from the literature review.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Metastasis of pulmonary adenocarcinoma to the oral cavity: A case report and literatures review of the last 30 years

Kawaharada

Maruyama

Abé

et al. 2022

Oral Science International

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Asoda¹,

Takamori²,

Uchiyama³

et al. 2009

J Jpn Soc Oral Tumor

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Thirteen tumors metastasizing in the oral and maxillofacial region were clinically investigated. Metastatic tumors accounted for 2.3％ of overall primary oral malignant tumors (573 cases). The mean age was 60.0 years with a range of 14 to 73 years old. Nine of the 13 patients were male and 4 were female. The primary sites of the tumors included lung (5) , kidney (3) , colon and rectum (2) , and 1 each in the stomach, mammary gland and adrenal gland. The locations of the metastasis included the soft tissues (10) and jaws (3). The usual symptoms of the metastatic lesions were well-demarcated swelling, and paresthesia of the mental region was noted in 2 cases of mandibular metastases. The histlogical types included adenocarcinoma (6) and 3 each for large cell carcinoma and renal cell carcinoma, and 1 for neuroblastoma. In 3 cases, the oral metastatic lesion was the first sign of the primary malignant tumor. In 6 cases, the primary tumor was controlled, but multiple metastases were recognized in all cases. Four cases were treated palliatively and radically respectively, but 5 cases did not received treatment after biopsy. In addition, in a review of the Japanese literature, 221 well-documented cases of metastatic tumors in the oral and maxillofacial region were analyzed. The most common primary organ was the lung (26.2％) followed by the liver (17.8％) , colon and rectum (9.5％) and kidney (9.0％). In 33.7％ of cases, the oral lesion was the first sign of the malignant disease.

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