2016
DOI: 10.14260/jemds/2016/457
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Clinical Study on Factors Influencing Wound Dehiscence in Emergency Exploratory Laparotomy

Abstract: BACKGROUNDWound dehiscence is a mental, financial and physical trauma to patients and has an equivalent effect on surgeon too. Wound dehiscence etches profound morbidity in a patient's life. There arises an expanding demand in the cost of care, both in terms of increased hospital stay and manpower in nursing and managing of burst wound and its complications. Thus understanding of factors contributing to dehiscence, correctable measures and precautionary steps are very much essential in day-to-day practice of a… Show more

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Cited by 4 publications
(4 citation statements)
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“…The incidence of wound complications is highest in subjects having pulmonary diseases (9 out of 12 patients ie 75%). These findings are comparable with the study of Talukdar M et al (15), in which out of total 213 patients 27 had wound dehiscence and its prevalence in anaemia, hypoalbuminemia, post-operative pulmonary complications, increased intraabdominal pressure, intra-abdominal sepsis/wound infection, delayed presentation and malignancy. So perioperative management of these co morbidities plays a major role in wound healing and complications.…”
Section: Observation and Resultssupporting
confidence: 90%
“…The incidence of wound complications is highest in subjects having pulmonary diseases (9 out of 12 patients ie 75%). These findings are comparable with the study of Talukdar M et al (15), in which out of total 213 patients 27 had wound dehiscence and its prevalence in anaemia, hypoalbuminemia, post-operative pulmonary complications, increased intraabdominal pressure, intra-abdominal sepsis/wound infection, delayed presentation and malignancy. So perioperative management of these co morbidities plays a major role in wound healing and complications.…”
Section: Observation and Resultssupporting
confidence: 90%
“…Kenig et al reported no significant differences between the study and control groups regarding anemia, which is synonymous with our study. Similar findings were reported by Talukdar et al [ 20 ]. However, van Ramshorst et al reported that 33% of cases were uremic [ 3 ].…”
Section: Discussionsupporting
confidence: 92%
“…Pasien dengan hipoalbuminemia (albumin <3,5g/dL) mempunyai kemungkinan 16 kali lebih besar untuk terjadinya dehisensi bila dibandingkan dengan yang memiliki kadar albumin normal. 21 Hipoproteinemia berhubungan dengan penyembuhan luka yang buruk karena terdapat penurunan sintesis kolagen pada luka operasi maupun tempat anastomosis. 22,23 Hipoproteinemia menghambat respon imun, yaitu aktivasi makrofag dan pembentukan granuloma.…”
Section: Metodeunclassified
“…24 Hipoproteinemia memperpanjang fase inflamasi dan menganggu fibroplasia, proliferasi pro-teoglikan, dan sintesis kolagen sehingga meng-hambat neoangiogenesis serta proses remodeling. 21 Anemia merupakan faktor yang berpengaruh pada penyembuhan luka yang buruk. Namun hal ini masih menjadi perdebatan.…”
Section: Metodeunclassified