Clinical Study on the Effect of Absorbable Membrane Applied to Guided Tissue Regeneration Technique.

Yamanouchi, Kazuya; Nakagawa, Taneaki; Seida, Kizuku; Saito, Atsushi; Yamada, Satoru; Hiwatashi, Kyoko; Setoguchi, Takashi; Chuman, Masahiko; Sueda, Takeshi

doi:10.2329/perio.36.884

Cited by 6 publications

(2 citation statements)

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“…Previous study by our group evaluated the long-term clinical outcomes of treatment with EMD in a private practice setting 17) . The mean CAL gain at 6 months was 3.6 mm, which was significantly greater than that (2.2 mm) observed in our study on guided tissue regeneration utilizing bioresorbable membrane 26) . The results of the present study were comparable to those of earlier studies reporting the efficacy of EMD therapy.…”

Section: Discussioncontrasting

confidence: 77%

Treatment of Periodontal Defects with Enamel Matrix Derivative: Clinical Evaluation at Early Healing Stages

Saitô

Hayakawa

Ota

et al. 2010

Bull. Tokyo Dent. Coll.

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The aim of this retrospective clinical study was to evaluate the treatment of intrabony periodontal defects with enamel matrix derivative (EMD) during the early stages of healing. Sixteen patients aged 38-77 years with a clinical diagnosis of chronic periodontitis were subjected to data analysis. A total of 25 teeth with various osseous defects received regenerative therapy with EMD, and were followed for a minimum of 6 months. Post-operative healing was uneventful in the majority of cases. Treatment of the intrabony defects with EMD led to a statistically significant improvement in the mean value of probing depth at 3 months compared with that at baseline (pϽ0.001). Mean values of attachment gain at 3 and 6 months were of clinical significance: ‫8.1ע6.3‬ mm and ‫5.1ע2.3‬ mm, respectively. Reduction in probing depth was achieved with minimal recession of gingival margin and was sustained over a time course of 6 months. A progressive increase in radiopacity, suggestive of initial signs of bone-fill, was observed by 6 months. In summary, the results suggest that treatment of intrabony defect with EMD induces favorable periodontal healing with a high level of predictability.

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Section: Discussioncontrasting

confidence: 77%

Treatment of Periodontal Defects with Enamel Matrix Derivative: Clinical Evaluation at Early Healing Stages

Saitô

Hayakawa

Ota

et al. 2010

Bull. Tokyo Dent. Coll.

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“…The observed improvement in PD (approximately 4 mm) was in accordance with the results from a multi-center study of 956 cases in Japan 23) . Mean value for CAL gain 6 months after EMD treatment was ‫43.1ע16.3‬ mm, which was significantly greater than that observed with bioresorbable membrane therapy (2.2 ‫9.1ע‬ mm), as we have previously reported 24) . Mean CAL gain at 1-year was ‫64.1ע93.3‬ mm.…”

Section: Discussionsupporting

confidence: 38%

Treatment of Intrabony Periodontal Defects with Enamel Matrix Derivative in Private Practice: A Long-term Retrospective Study

Saitô

Nanbu²,

Nagahata³

et al. 2008

Bull. Tokyo Dent. Coll.

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The present study describes treatment of intrabony periodontal defects with enamel matrix derivative (EMD) in private practice. Ten patients with clinical diagnosis of chronic periodontitis were subjected to data analysis. A total of 18 teeth with various osseous defects received regenerative therapy with EMD, and were followed for a minimum of 2 years. Treatment of the intrabony defects with EMD led to a statistically significant improvement in the mean value of probing depth at 1-year when compared with at the baseline (pϽ0.01). Reduction in probing depth was achieved with minimal recession of the gingival margin, and was maintained over the 2-year observation period with no significant change. Mean values of attachment gain at 1 and 2 years were of clinical significance: ‫64.1ע93.3‬ mm and ‫04.1ע22.3‬ mm, respectively. Although one tooth was extracted because of subsequent loss of attachment and bone, most teeth treated have been successfully maintained for 2 to 7 years with no significant signs of disease progression. In conclusion, EMD treatment of intrabony osseous defects yielded clinically favorable responses. The gain in clinical attachment can be longitudinally maintained in a private practice setting. Further controlled studies are needed to elucidate the clinical significance of EMD treatment.

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Clinical study of guided bone regeneration with resorbable polylactide-co-glycolide acid membrane

et al. 2018

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The guided bone regeneration (GBR) technique is often applied to provide sufficient bone for ideal implant placement. The objective of this study was to evaluate whether GC membrane, which has already been used for guided tissue regeneration (GTR), can also be available for GBR. Twenty-three implants in 18 patients were evaluated in the study. All patients underwent implant placement with GBR using GC membrane. Cone-beam computed tomography was performed at 13-30 weeks after surgery and the amount of augmented bone was assessed. The implant stability quotient (ISQ) was measured at the second operation to evaluate implant stability. Although wound dehiscence was observed at 4 of 23 regions (17.4%), all wounds closed quickly without any events by additional antibiotic administration. GBR-induced bone augmentation of 0.70-2.56 mm horizontally and 0-6.82 mm vertically. Only 0.18 mm of bone recession was observed at 16-24 months after implant placement. GBR with GC membrane induced sufficient bone augmentation, leading to successful implant treatment. The present results suggest that GC membrane is available not only for GTR, but also for GBR.

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Clinical Study on the Effect of Absorbable Membrane Applied to Guided Tissue Regeneration Technique.

Cited by 6 publications

References 0 publications

Treatment of Periodontal Defects with Enamel Matrix Derivative: Clinical Evaluation at Early Healing Stages

Treatment of Periodontal Defects with Enamel Matrix Derivative: Clinical Evaluation at Early Healing Stages

Treatment of Intrabony Periodontal Defects with Enamel Matrix Derivative in Private Practice: A Long-term Retrospective Study

Clinical study of guided bone regeneration with resorbable polylactide-co-glycolide acid membrane

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