2024
DOI: 10.1007/s00415-024-12366-5
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Clinical trial evidence of quality-of-life effects of disease-modifying therapies for multiple sclerosis: a systematic analysis

Julian Hirt,
Kinga Dembowska,
Tim Woelfle
et al.

Abstract: Background Increasingly, patients, clinicians, and regulators call for more evidence on the impact of innovative medicines on quality of life (QoL). We assessed the effects of disease-modifying therapies (DMTs) on QoL in people with multiple sclerosis (PwMS). Methods Randomized trials assessing approved DMTs in PwMS with results for at least one outcome referred to as “quality of life” were searched in PubMed and ClinicalTrials.gov. … Show more

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