1995
DOI: 10.1016/0003-4975(95)00407-c
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Clinical trial of tacrolimus versus cyclosporine in lung transplantation

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Cited by 216 publications
(113 citation statements)
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References 7 publications
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“…The median number of tacrolimus measurements per patient for the 0-6, 6-12 and 12-24 month periods were 15 (IQR 8 -24), 11 (7-17, range 2-30 measurements) and 13 (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) respectively. There was a positive correlation between the number of tacrolimus measurements and trough level SD (r = 0.489 p<0.001, Figure 3) but not with the mean (p=0.698).…”
Section: Tacrolimus Mean and Sdmentioning
confidence: 99%
See 1 more Smart Citation
“…The median number of tacrolimus measurements per patient for the 0-6, 6-12 and 12-24 month periods were 15 (IQR 8 -24), 11 (7-17, range 2-30 measurements) and 13 (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) respectively. There was a positive correlation between the number of tacrolimus measurements and trough level SD (r = 0.489 p<0.001, Figure 3) but not with the mean (p=0.698).…”
Section: Tacrolimus Mean and Sdmentioning
confidence: 99%
“…Of these agents, cyclosporine led to the biggest stepchange in the success of solid organ transplantation, with more recent evidence supporting a slight advantage for tacrolimus over cyclosporine in lung transplantation (11)(12)(13)(14)(15)(16).…”
Section: Introductionmentioning
confidence: 99%
“…KEENAN and co-workers [42,43] randomised 133 recipients to receive either CsA or Tac combined with Aza and steroids. Less acute rejection episodes and significantly less BOS (38% versus 22%) were observed in the Tac group.…”
Section: Maintenance Therapymentioning
confidence: 99%
“…Heart and lung, transplant recipients have not been systematically studied to define precisely the magnitude of nephrotoxicity in that in that patient population (46,47) The wide range in reported incidence depends not only on the dosing regimen but also on prior clinical experience with the drug (11,17). Thus, the Japanese multicenter study recorded a 44% incidence, of nephrotoxicity when tacrolimus was administered at a dose of 0.3, mg/kg/day.…”
Section: Clinical Features Of Tacrolimus Nephrotoxicitymentioning
confidence: 99%