Clinical update on metabolic syndrome

Hernández-Camacho, Juan Diego; Hernández-Camacho, Miguel

doi:10.14306/renhyd.21.4.392

Cited by 6 publications

(3 citation statements)

References 51 publications

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“…The highest percentage of obese women occurs in the menopausal period [3]. Menopausal women are most often characterised by abdominal obesity, also known as android or visceral obesity [4,5]. In menopausal women, the increase in BMI and total body mass, which consists of fat mass and the remaining tissues (lean body mass), is mainly due to an increase of fat in the abdominal area.…”

Section: Introductionmentioning

confidence: 99%

Whole-Body Cryotherapy Is an Effective Method of Reducing Abdominal Obesity in Menopausal Women with Metabolic Syndrome

Więcek

Szymura

Sproull

et al. 2020

JCM

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Abdominal obesity predominates in menopausal women (MW) and contributes to the development of metabolic syndrome (MetS). It is associated with increased mortality related to cardiovascular disease, diabetes and fatty liver disease. The effects of whole-body cryotherapy (WBC) on body composition and the blood concentration of irisin, interleukin-6 (IL-6) and C-reactive proteins (CRP) in MW with MetS and in healthy women (HW), were assessed. The study included 19 women with MetS (61.53 ± 3.99 y, BMI 30.09 ± 4.98 kg/m2) and 18 HW (60.28 ± 3.63 y, BMI 25.50 ± 2.37 kg/m2) who were subjected to 20 WBC treatments at −130 °C for 3 min daily. In both groups, body mass (BM), BMI, abdominal circumference, triceps skinfold, total fat mass and percentage of leg fat significantly decreased after 20 WBC sessions. Additionally, the percentage of total, trunk and android fat in the MetS group were significantly decreased after 20 WBC applications. Waist circumference (WC) and waist-to-height ratio (WHtR) significantly decreased in both groups, and in the HW group, hip circumference and abdominal skinfold also significantly decreased after 10 WBC and 20 WBC treatments. In both groups, the concentration of plasma irisin significantly increased after 1 WBC and 10 WBC exposures, while the concentration of IL-6 significantly increased only in MetS group after 10 WBC and 20 WBC, and were significantly higher than in HW. CRP concentrations were significantly higher in the MetS group than in HW before 1 WBC, after 1 WBC and 10 WBC sessions, but not after 20. In the MetS group, there were significant negative correlations between the change in irisin level and the changes in WC and BM, and between the level of irisin and the change in percentage of total fat, and significant negative correlations between the change in IL-6 level and changes in WC, waist-to-hip ratio and WHtR. Whole-body cryotherapy, assuming the application of 20 treatments in the series, reduces abdominal obesity in menopausal women indirectly through the secretion of irisin and IL-6, and can be used as adjunctive therapy in the treatment of metabolic syndrome. Our conclusion is limited to menopausal women with low–moderate physical activity for whom its level as well as diet were not changed during the treatment.

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Section: Introductionmentioning

confidence: 99%

Whole-Body Cryotherapy Is an Effective Method of Reducing Abdominal Obesity in Menopausal Women with Metabolic Syndrome

Więcek

Szymura

Sproull

et al. 2020

JCM

View full text Add to dashboard Cite

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“…Metabolic syndrome is a group of clinical, metabolic and biochemical abnormalities with negative impact on global health. 1 Based on the International Diabetes Federation (IDF) consensus statement, it is defined as the presence of body mass index >30 kg/m 2 with any two of the following: triglycerides ≥1.7 mmol/l, high-density lipoprotein <1.29 mmol/l, hypertension (systolic BP ≥130 or diastolic BP ≥85 mmHg) or fasting blood glucose ≥100 mg/dl or 5.6 mmol/l. 3 Normal pregnancy adaptations to cater for nutritional needs of the growing foetus induces cardiometabolic stress reminiscent of metabolic syndrome with increased insulin resistance, hyperlipidaemias and changes in protein and amino acid metabolism.…”

Section: Introductionmentioning

confidence: 99%

Association of metabolic syndrome with gestational hypertension

Khan,

Basit,

Ahmed

2024

Int J Reprod Contracept Obstet Gynecol

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Background: Metabolic syndrome is a group of clinical, metabolic and biochemical abnormalities with negative impact on global health. The aim of the study was to determine the association between metabolic syndrome and pregnancy induced hypertension, and incidence and effects of metabolic syndrome in pregnant patients. Methods: Prospective observational study, performed in the Department of Obstetrics and Gynecology, Holy Family Hospital, New Delhi. Antenatal women before 20 weeks of gestation were enrolled in the study. Metabolic syndrome was diagnosed by utilizing the pregnancy adaptation of MeS criteria of NCEPATP III laboratory and clinical criteria. Cases were followed throughout pregnancy to observe their progression into hypertensive disorders of pregnancy i.e. gestational hypertension, pre-eclampsia and eclampsia. Results: Out of 100 cases with metabolic syndrome 37% developed PIH, 21 developed pre-eclampsia and 14 developed gestational hypertension, 2 patients developed eclampsia as compared to controls in which only 10% developed PIH among which only 3% developed pre-eclampsia. Conclusions: Our study demonstrates a higher rate of complicated pregnancy with higher incidence of PIH in association with metabolic syndrome compared to control group. Each component of metabolic syndrome increases the probability of PIH. The addition of components of metabolic syndrome exacerbates this probability, especially the combination of increased BMI, increased blood sugar levels and increased triglycerides.

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“…Estimations from the Global Burden of Diseases indicate that, in 2015, 19.4% and 8.2% of the world population were exposed to high systolic blood pressure and high fasting plasma glucose, respectively, being responsible of 16 million of global deaths 1 . Issues such as age, gender, genetic background, physical activity, dietary patterns and microbiota composition have been associated with these MetS risk factors 2 . Hypocaloric and low-salt diets are first strategies to control both hypertension and glycaemia 3 .…”

Section: Introductionmentioning

confidence: 99%