Clinical usability of the Story-Based Empathy Task (SET) in non-demented ALS patients

Aiello, Edoardo Nicolò; Solca, Federica; Torre, Silvia; Colombo, Eleonora; Maranzano, Alessio; Olivero, Marco; Scheveger, Francesco; Morelli, Claudia; Doretti, Alberto; Verde, Federico; Ferrucci, Roberta; Barbieri, S.; Mameli, Francesca; Priori, Alberto; Silani, Vincenzo; Ticozzi, Nicola; Poletti, Barbara

doi:10.1007/s10072-023-06791-z

Cited by 2 publications

(1 citation statement)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, patients were assessed for global cognition [Edinburgh Cognitive and Behavioral ALS Screen, ECAS (Poletti et al, 2016 )], executive [Frontal Assessment Battery, FAB (Appollonio et al, 2005 ; Aiello et al, 2023a )], social-cognitive functions [Reading the Mind in the Eyes Test, RMET (Aiello et al, 2022 ; Maddaluno et al, 2022 ); Emotion Attribution subtest of the Story-Based Empathy Task, SET-EA (Dodich et al, 2015 ; Aiello et al, 2023b )], behavior [State- and Trait-Anxiety Inventory-Form Y, STAI-Y1/-Y2 (Spielberger et al, 1971 ); Beck Depression Inventory, BDI (Beck et al, 1961 ); Beaumont Behavioral Inventory, BBI (Iazzolino et al, 2022 ); Dimensional Apathy Scale, DAS (Santangelo et al, 2017 )], and motor-functional status [ALS Functional Rating Scale-Revised, ALSFRS-R (Cedarbaum et al, 1999 )]. Progression rate (ΔFS) was computed as (48-ALSFRS-R score)/disease duration in months (Kimura et al, 2006 ), and disease staging was retrieved via King's (Roche et al, 2012 ) and Milano-Torino (MiToS) (Chiò et al, 2015 ) systems.…”

Section: Methodsmentioning

confidence: 99%

An exploratory study on counterfactual thinking in amyotrophic lateral sclerosis

Poletti,

Aiello,

Tagini

et al. 2023

Front. Psychol.

Self Cite

View full text Add to dashboard Cite

ObjectivesThis study aimed at exploring (1) the motor and non-motor correlates of counterfactual thinking (CFT) abilities in non-demented amyotrophic lateral sclerosis (ALS) patients and (2) the ability of CFT measures to discriminate these patients from healthy controls (HCs) and patients with and without cognitive impairment.MethodsN = 110 ALS patients and N = 51 HCs were administered two CFT tasks, whose sum, resulting in a CFT Index (CFTI), was addressed as the outcome. Patients further underwent an in-depth cognitive, behavioral, and motor-functional evaluation. Correlational analyses were run to explore the correlates of the CFTI in patients. Logistic regressions were performed to test whether the CFTI could discriminate patients from HCs.ResultsThe CFTI was selectively associated (p ≤ 0.005) with fluency and memory subscales of the Edinburgh Cognitive and Behavioral ALS Screen (ECAS), but not with other variables. CFTI scores discriminated patients from HCs (p < 0.001) with high accuracy (82%), but not patients with a normal vs. defective performance on the ECAS-Total.ConclusionCFT measures in non-demented ALS patients were associated with verbal fluency and memory functions, and they were also able to discriminate them from HCs.

show abstract

Section: Methodsmentioning

confidence: 99%

An exploratory study on counterfactual thinking in amyotrophic lateral sclerosis

Poletti,

Aiello,

Tagini

et al. 2023

Front. Psychol.

Self Cite

View full text Add to dashboard Cite

show abstract

Describing and assessing behavioural symptoms in amyotrophic lateral sclerosis with and without frontotemporal dementia: a scoping review

Trucco,

Backhouse,

Mioshi

2024

Current Opinion in Neurology

View full text Add to dashboard Cite

Purpose of review Alongside motor and cognitive symptoms, amyotrophic lateral sclerosis (ALS) and ALS with frontotemporal dementia (ALSFTD) present with behavioural symptoms, which can be challenging for all affected by the disease. A scoping review of studies published between 2011 and 2024 was conducted to present the breadth of behavioural symptoms in ALS and ALSFTD, explore how they are described and assessed, and identify patterns in the literature. Findings This scoping review identified 3939 articles, with 111/3939 meeting eligibility criteria. Most studies were from Australia (23.22%), Italy (16.94%) and the UK (14.29%); 75.67% were cross-sectional. Sample size ranged from 1 to 1013, as case studies were included. Overall mean age (100/111 studies) was 61.32 (SD = 4.15). Proportion of male patients (reported 102/111 studies) was 61.49%; mean disease duration (reported in 86/111 records) was 32.63 months (SD = 24.72). Papers described a broad range of behavioural symptoms (465 examples), which were thematically collated into seven categories: disinhibition (27.74%), apathy (25.16%), perseverative/compulsive behaviours (17.42%), hyperorality (10.53%), loss of sympathy or empathy (8.6%), psychotic symptoms (7.74%), and loss of insight about disease and changes (2.8%). Most studies (78.37%) used validated behavioural assessments that elicited carer's perspectives. Summary Despite extensive evidence of behavioural symptoms in ALS, implementation of assessments and management of behavioural symptoms in clinical care remain limited. Clinicians must assess behavioural symptoms, as these can negatively affect disease prognosis, patient treatment engagement and increase family distress. Measures capturing carers’ perspectives through interviews are ideal as they can reveal anosognosia, lack of sympathy and lack of empathy.

show abstract

Clinical usability of the Story-Based Empathy Task (SET) in non-demented ALS patients

Cited by 2 publications

References 33 publications

An exploratory study on counterfactual thinking in amyotrophic lateral sclerosis

An exploratory study on counterfactual thinking in amyotrophic lateral sclerosis

Describing and assessing behavioural symptoms in amyotrophic lateral sclerosis with and without frontotemporal dementia: a scoping review

Contact Info

Product

Resources

About