Clinical use of copeptin in migraine patients admitted to the emergency department

Investigation of the plasma copeptin level in cases with childhood migraine

“…Another study by Blum et al 22 reported that copeptin level was higher in patients with severe secondary headache compared to benign forms of headache, and there was a positive correlation between them. In a study conducted by Yılmaz et al 23 on adults recently, a significant difference was found in the mean copeptin level in migraine patients in the periods with and without migraine attacks; however, but its strength in clinical diagnosis was not satisfactory. In our current study, the median plasma copeptin level was 298.25 pg/mL in the patient group, while it was 194.35 pg/mL in the control group (p < 0.001).…”

“…The diagnostic value of copeptin and its relationship with headache have been the subject of research, especially in the recent past in pathological cases that may have been associated with headache. 21– 23 Zuo and Ji 21 expressed that copeptin levels can reliably predict short-term prognosis at the onset of aneurysmal subarachnoid hemorrhage in patients. Another study by Blum et al 22 reported that copeptin level was higher in patients with severe secondary headache compared to benign forms of headache, and there was a positive correlation between them.…”

“…[18][19][20] On the other hand, the diagnostic value of copeptin has also been shown in various diseases in the adults, such as non-traumatic headaches, migraine, strokes, subarachnoid hemorrhages, and traumatic brain injuries, which may be correlated with headache. [21][22][23] The aim of this research was to determine the copeptin level in migraine patients in childhood and to investigate its relationship with oxidative stress level.…”