Clinical utility of ozone therapy for musculoskeletal disorders

Abstract

Oxygen-ozone (O3) therapy serves as an alternative medical technique that increases the oxygen in the body along with the introduction of O3. O3 therapy has finally reached a level where the biological mechanisms of action have been understood, showing that they are in the domain of physiology, biochemistry, and pharmacology. Few clinical applications have been reviewed here as well as exemplifying that O3 therapy is particularly useful in musculoskeletal disorders. In the therapeutic range, O3 can be used as a more effective and safe substitute of standard medications. O3 therapy has been used for many years for its ability to inactivate various viruses, cancer, and acquired immune deficiency syndrome but is now making strides in the treatment of musculoskeletal disorders such as rheumatoid arthritis, lumbar facet joint syndrome, subacromial bursitis, carpal tunnel syndrome, osteoarthritis, hip bursitis, shoulder adhesive capsulitis, herniated disc, and temporomandibular joint disorder.

Ultrasound-Guided Intra-Articular Ozone Injection as a Therapeutic Option for Hip Osteonecrosis

“…6 There is a limited number of clinical studies in literature about the effectiveness of ozone in the management of musculoskeletal diseases. 7 The common view in these previous studies is that local ozone therapy has positive results in the regenerative process. [6][7][8] It is mainly recommended for patients with low back pain, osteoarthritic pain (knee, hip, shoulder, etc.…”

“…7 The common view in these previous studies is that local ozone therapy has positive results in the regenerative process. [6][7][8] It is mainly recommended for patients with low back pain, osteoarthritic pain (knee, hip, shoulder, etc. ), inflammatory diseases and to deal with symptoms of the diabetic foot.…”

“…Ozone therapy is used to alleviate hip pain due to functional overload, pain caused by primary or secondary coxarthrosis, bursitis and tendinitis. 7 Ozone therapy is effective in hip osteonecrosis, which is a condition in which conventional medical approaches are not very effective and the risk of hip surgery is high. 14 Ozone therapy may also help to delay the need for hip arthroplasty.…”

<p>Ozone Therapy and Aquatic Rehabilitation Exercises to Overcome the Lumbar Pain Caused by Facet Joint Syndrome – Case Report</p>

“…[17][18][19] OT could be efficacious against spinal-degeneration diseases as well as acute and chronic inflammation. 6 In LBP due to lumbar-disk herniation or FJS, OT could be an efficacious and valid alternative to conservative treatments that have failed. [25][26][27] In FJS, the synovial villi within facet joints can become inflamed or trapped between articular processes, thereby producing pain, and OT can help to reduce such pain.…”

“…FJS has been shown to be the culprit in 15-45% of patients with LBP: typically, there is more discomfort while leaning backward than while leaning forward. [6][7][8] FJS is a painful irritation of the posterior part of the lumbar spine and swelling from the surrounding structures, and can cause pain due to irritation of nerve roots. Selective anesthesia of the medial branch of the dorsal primary ramus of the spinal nerve innervating the facet joint can be undertaken to diagnose FJS.…”