Clinical value of gallium‐67 SPECT scintigraphy in the diagnostic and therapeutic evaluation of retroperitoneal fibrosis: a prospective study

Bommel, E. F. H. van; Siemes, Claire; Veer, Sacha J. van der; Han, Sangwon; Huiskes, A. W. L. C.; Hendriksz, Tadek R

doi:10.1111/j.1365-2796.2007.01805.x

Cited by 21 publications

(9 citation statements)

References 22 publications

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“…At present, there are no validated predictors of response to glucocorticoids. Gallium scanning has been proposed to help in predicting such a response (21), but a recent study showed that such scanning failed to discriminate between responders and nonresponders to prednisone (15). There is a general belief that an elevated ESR and an elevated CRP level at the time of diagnosis reflect active inflammation, indicating that glucocorticoid therapy might be effective.…”

Section: Introductionmentioning

confidence: 99%

Do acute‐phase reactants predict response to glucocorticoid therapy in retroperitoneal fibrosis?

Magrey

Husni

Kushner

et al. 2009

Arthritis & Rheumatism

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Objective. To determine the value of the erythrocyte sedimentation rate (ESR) and the C-reactive protein (CRP) level at the time of diagnosis for predicting radiographic response to glucocorticoid therapy in patients with retroperitoneal fibrosis (RFP). Methods. Data were collected retrospectively for 37 patients with an established diagnosis of RFP (the diagnosis was proven by biopsy in 31 patients), all of whom met the following inclusion criteria: 1) availability of a recorded baseline ESR and/or CRP level and results of computed tomography or magnetic resonance imaging, 2) availability of followup CRP level and/or ESR with radiographic imaging 12-24 weeks after initiation of therapy, and 3) treatment with prednisone monotherapy at a starting dosage of 40 -60 mg daily. Patients were divided into 2 therapeutic response groups: group 1 showed radiographic regression, and group 2 showed no change or radiographic progression. Any progression or regression was determined by an estimated change of >25%.

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Section: Introductionmentioning

confidence: 99%

Do acute‐phase reactants predict response to glucocorticoid therapy in retroperitoneal fibrosis?

Magrey

Husni

Kushner

et al. 2009

Arthritis & Rheumatism

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“…Scintigraphy using gallium-67 is positive in about 70% of patients with retroperitoneal fibrosis and is used to assess recurrent disease in these patients. 8 Positron emission tomography using fluorine-18 fludeoxyglucose is also useful for monitoring active inflammation within the fibrotic soft tissue. 9…”

Section: Figmentioning

confidence: 99%

An unusual cause of acute renal failure

Dilks

Shawyer

Booth

2009

BMJ

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“…Repeat CT scanning showed a large peri-aortic mass; gallium-67 scanning revealed intense pathologic activity. 46 Treatment was started with prednisone and cyclophosphamide, which led to rapid improvement. At the time of his latest follow-up, a second recurrence after surgical intervention necessitated re-introduction of immunosuppressive treatment.…”

Section: Casementioning

confidence: 99%

“…Gallium scanning was negative. 46 Recurrent chronic peri-aortitis despite aneurysmectomy was suspected. Chronic kidney disease was thought to be due to chronic hypertension and generalized vascular disease.…”

Section: Casementioning

confidence: 99%

Persistent chronic peri-aortitis (‘inflammatory aneurysm’) after abdominal aortic aneurysm repair: systematic review of the literature

et al. 2008

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Data on the outcome of aneurysmal chronic peri-aortitis ('inflammatory aneurysm') after open surgical aneurysm repair are few and contradictory. To what extent this inflammatory process is reversed after endovascular aneurysm repair (EVAR) is even more unclear. The objective of this review was to study the outcome of peri-aortic fibrosis (PAF) and ureteral obstruction in patients with aneurysmal chronic peri-aortitis treated with open surgery or EVAR. Medical literature was searched for pertinent articles on the outcome of PAF and ureteral obstruction after open surgery or EVAR from 1970 through October 2007. Studies were included if specific follow-up data were available on outcomes of interest. A total of 19 studies were included comprising 478 patients (open surgical, n = 426; EVAR, n = 52). Age, sex and percentage of patients with ureteral obstruction (31% vs 37%) did not differ between groups. Regression of PAF occurred more frequently after open surgery compared to EVAR (86% vs 60%; p < 0.0001). Complete regression of PAF was more frequent after open surgery compared to EVAR (52% vs 14%; p < 0.0001). After excluding patients in whom concurrent ureterolysis was performed, the frequency of persistent ureteral obstruction remained lower in patients treated surgically compared to patients treated with EVAR, albeit not statistically significant (32% vs 56%; p = 0.09). In conclusion, although open surgery is superior to EVAR in achieving regression of chronic periaortitis, the frequency of persistent PAF and/or ureteral obstruction is not negligible. Additional medical and/or urological treatment should be considered in selected cases of aneurysmal chronic peri-aortitis.

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Clinical value of gallium‐67 SPECT scintigraphy in the diagnostic and therapeutic evaluation of retroperitoneal fibrosis: a prospective study

Cited by 21 publications

References 22 publications

Do acute‐phase reactants predict response to glucocorticoid therapy in retroperitoneal fibrosis?

Do acute‐phase reactants predict response to glucocorticoid therapy in retroperitoneal fibrosis?

An unusual cause of acute renal failure

Persistent chronic peri-aortitis (‘inflammatory aneurysm’) after abdominal aortic aneurysm repair: systematic review of the literature

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