Clinical value of total white blood cells and neutrophil counts in patients with suspected appendicitis: retrospective study

Al-Gaithy, Zuhoor K

doi:10.1186/1749-7922-7-32

Cited by 43 publications

(38 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“… 11 , 12 In several published studies, the sensitivity and specificity of LC in the diagnosis of AA has been reported as 67%-97.8% and 31.9%-80%, respectively. 13 , 14 The present study found that LC was significantly higher in AA, and the sensitivity and specificity of LC were 94% and 75%, respectively.…”

Section: Discussionsupporting

confidence: 45%

Mean Platelet Volume is Reduced in Acute Appendicitis

Küçük

Kucuk

2015

Turkish Journal of Emergency Medicine

View full text Add to dashboard Cite

SUMMARYObjectivesAcute appendicitis (AA) is the most common indication for emergency abdominal surgery, although it remains difficult to diagnose. In this study, we investigated the the clinical utility of mean platelet volume in the diagnosis of acute appendicitis.MethodsThe medical records of 241 patients who had undergone appendectomy between June 2013 and March 2014 were investigated retrospectively. Sixty patients who had undergone at least one complete blood count during preoperative hospital admission and who had no other active inflammatory conditions at the time the sample was taken were included in the study. Mean platelet volume and leukocyte count values were determined in each patient at hospital admission and during active acute appendicitis. Age, sex, mean platelet volume and leukocyte counts were recorded for each patient.ResultsThe mean age of patients was 33.15±10.94 years and the male to female ratio was 1.5:1. The mean leukocyte count prior to acute appendicitis was 7.42±2.12×103/mm3. Mean leukocyte count was significantly higher (13.14±2.99×103/mm3) in acute appendicitis. The optimal leukocyte count cutoff point for the diagnosis of acute appendicitis was 10.10×103/mm3, with sensitivity of 94% and a specificity of 75%. The mean platelet volume prior to acute appendicitis was 7.58±1.11 fL. Mean platelet volume was significantly lower (7.03±0.8 fL) in acute appendicitis. The optimal mean platelet volume cutoff point for the diagnosis of AA was 6.10 fL, with a sensitivity of 83% and a specificity of 42%. Area under the curve for leukocyte count diagnosis was 0.67 and 0.69 for the diagnosis of AA by mean platelet volume.ConclusionsMean platelet volume was significantly decreased in acute appendicitis. Mean platelet volume can be used as a supportive diagnostic parameter in the diagnosis of acute appendicitis.

show abstract

Section: Discussionsupporting

confidence: 45%

Mean Platelet Volume is Reduced in Acute Appendicitis

Küçük

Kucuk

2015

Turkish Journal of Emergency Medicine

View full text Add to dashboard Cite

show abstract

“…Studies done in the United States, California University, NA rate was (9%). In Saudi Arabia, Arar central hospital NA rate was (3%), and In Jeddah KAUH 2012 NAR was (6.4%) ( 17 - 19 ). A study was done in Riyadh, in the period 1998-2003 found those 23±8.67 years is the mean age-associated more with NA ( 20 ).…”

Section: Discussionmentioning

confidence: 97%

Negative Appendectomy Rate and Risk Factors That Influence Improper Diagnosis at King Abdulaziz University Hospital

Alhamdani¹,

Rizk²,

Algethami³

et al. 2018

Mater Sociomed

View full text Add to dashboard Cite

Introduction:Acute Appendicitis is the most common emergent abdominal surgery worldwide. diagnosis based on clinical assessment, laboratory and radiological investigations and appendectomy is the treatment of choice. Removing a normal appendix is a relatively common surgical issue, defined as negative appendectomy (NA). Multiple risk factors contribute to NA; female gender, normal WBC, normal CRP count, and CT scan unavailability. However, recently NA is decreasing in incidence after CT scan and Alvarado scoring.Aim:We aimed to estimate the rate of negative appendectomy, and determine possible risk factors among King Abdulaziz University Hospital.Patients and Methods:Article has a retrospective character and included non-incidental 441 patients who undergo an appendectomy, during period 2008 to 2018.Results:Negative Appendectomy incidence (9.5%) was higher among females at (64.3%). Gynecological complaints were seen in (22.2%) of cases with a sign for Negative Appendectomy. Surgery reports documented (29.6%) of female ovarian cyst diseases. Alvarado scoring at presentation was less than 7 in (69%) of cases with statistical significance value. Normal WBC count (50%), for automated neutrophil (45.2%) was high, and same number were recorded with the normal neutrophil count, all of them have statically significant relation with NA.Conclusion:Proper clinical evaluation involves documenting Alvarado score, using CRP, efficient radiological utilization. Also, considering more referrals to gynecological specialists of similar presentation especially females at reproductive age. Investing in time and equipment for proper clinical assessment can avoid the unnecessary burden and save our resources for better use.

show abstract

“…Al-Gaithy et al [12] have studied four hundred and fifty-six patients with appendicitis while trying to determine the diagnostic value of leucocyte count and neutrophil ratio and the relation of these inflammatory markers with the severity of acute appendicitis. They have stated that leukocyte and neutrophil counts cannot be used as single diagnostic tests for acute appendicitis.…”

Section: Discussionmentioning

confidence: 99%