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Background: Most children undergoing chemotherapy for cancer experience gastrointestinal (GI) tract symptoms that affect their eating habits, nutritional status, and quality of life (QOL). Previous research on the connections between these factors has primarily focused on Western countries. As a result, there is limited understanding of these issues among Thai children. Objective: To describe GI symptoms, eating, nutritional status, and QOL for Thai children with cancer. Methods: This descriptive study used multiple methods. Quantitative data were collected through (1) standardized measures of GI symptoms and QOL and (2) extraction of medical history and clinical data from the child’s medical records, then analyzed using descriptive statistics. Qualitative data were collected with semistructured interviews with each child, then their parent, and analyzed using a directed content analysis. Results: Sixteen child-parent dyads participated in this study. Most children exhibited reduced food intake and weight loss, primarily attributed to GI symptoms and environmental factors. Underreporting of symptoms was identified, contributing to suboptimal symptom management. Clinician-recommended low-bacterial diets posed challenges to maintaining children’s food intake. Additionally, hospital food with repetitive menus and plain flavors was generally undesirable for children during hospitalization. Conclusions: Multifaceted factors influencing the nutritional status and QOL of children with cancer within the unique care context of Thailand were identified. Implications for Practice: The study findings inform the development of multi-level interventions targeting to optimize eating, nutritional status, and QOL for children with cancer. What is Foundational: The model, informed by cultural considerations, could be adapted for research in other countries with distinctive cultures.
Background: Most children undergoing chemotherapy for cancer experience gastrointestinal (GI) tract symptoms that affect their eating habits, nutritional status, and quality of life (QOL). Previous research on the connections between these factors has primarily focused on Western countries. As a result, there is limited understanding of these issues among Thai children. Objective: To describe GI symptoms, eating, nutritional status, and QOL for Thai children with cancer. Methods: This descriptive study used multiple methods. Quantitative data were collected through (1) standardized measures of GI symptoms and QOL and (2) extraction of medical history and clinical data from the child’s medical records, then analyzed using descriptive statistics. Qualitative data were collected with semistructured interviews with each child, then their parent, and analyzed using a directed content analysis. Results: Sixteen child-parent dyads participated in this study. Most children exhibited reduced food intake and weight loss, primarily attributed to GI symptoms and environmental factors. Underreporting of symptoms was identified, contributing to suboptimal symptom management. Clinician-recommended low-bacterial diets posed challenges to maintaining children’s food intake. Additionally, hospital food with repetitive menus and plain flavors was generally undesirable for children during hospitalization. Conclusions: Multifaceted factors influencing the nutritional status and QOL of children with cancer within the unique care context of Thailand were identified. Implications for Practice: The study findings inform the development of multi-level interventions targeting to optimize eating, nutritional status, and QOL for children with cancer. What is Foundational: The model, informed by cultural considerations, could be adapted for research in other countries with distinctive cultures.
Objective: The objective of this review is to synthesize the experiences of informal caregivers’ feeding practices for children with cancer. Introduction: Changes in eating among children with cancer impact their nutritional status, leading to several negative outcomes. In addition to interventions given by health care providers, informal caregivers’ experiences in feeding these children are worth exploring. Inclusion criteria: This review will include qualitative studies or the qualitative component of mixed method studies examining informal caregivers’ experiences of feeding children with cancer under 18 years old, published in English or Thai in any year up to the present. Methods: This review will follow the JBI approach for qualitative systematic reviews. A full search strategy for MEDLINE (PubMed) was developed from an initial limited search of MEDLINE (PubMed) and CINAHL (EBSCOhost) to identify articles on the topic. The search strategy will be adapted for each database, including Embase (Ovid), MEDLINE (PubMed), CINAHL (EBSCOhost), Cochrane Library (CENTRAL), LILACS (BVS), PsycINFO (Ovid), Web of Science, Scopus, and ThaiJO (TCI). The reference lists of studies included in the review will be hand-searched for additional studies. Sources of unpublished studies and gray literature will also be searched. Two reviewers will separately screen for eligible studies, perform the critical appraisal, and extract data. They will then synthesize via meta-aggregation and summarize the data. The final synthesized findings will be graded using the ConQual approach to establish confidence in the qualitative research synthesis. Review registration: PROSPERO CRD42024501382
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