Clinico Histopathological Overview of GIT Lesions in a Rural Hospital

Thakur, Rajesh Y; Nikumbh, Dhiraj B.; Swami, Sunil Y

doi:10.5958/2394-6792.2016.00058.2

Cited by 8 publications

(11 citation statements)

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“…This is similar to results of McCleary et al 25 study in USA which showed that GIT malignant tumors were more prevalent among elderly population (>70 years age).Present study showed that male gender was significantly associated with malignant GIT tumors (p=0.04). This finding coincides with results of Thakur et al 26 study in India which showed a male preponderance for all sites in the gastrointestinal tract with 34 (64.0%) male patients and 19 (36.0%) female patients.…”

Section: Discussionsupporting

confidence: 92%

Role of Endoscopic Ultrasound Guided Fine Needle Aspirate for Evaluating Lesions in or Adjacent to Gastrointestinal Tract: A Single Tertiary Care Center Experience

2020

MLU

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Background: Endoscopic ultrasonography guided-fine needle aspiration offers through linear endoscopy an opportunity for sampling mediastinal, intra-abdominal, pancreatic and pelvic lesions under direct visualization. Aim of Study:To assess the validity of endoscopic ultrasonography guided-fine needle aspiration from patients with gastrointestinal tract disorder discovered by endoscopy or other imaging modalities in comparison to histopathology. Patients and Method:A retrospective data review study conducted in Kurdistan Center for Gastroenterology & Hepatology in Sulaimani through the period from 1 st of January 2016 to 31 st of December 2016 onsample of 102 suspected gastrointestinal tumors patients. Endoscopic ultrasonography data base at Kurdistan Center during 4 years period (January 2013-December 2016) is searched for all patients referred for Endoscopic ultrasonography-fine needle aspiration.Results: Endoscopic ultrasonography showed that 51% of suspected gastrointestinal tumor patients had malignancy while histopathology showed that 45.1% of suspected patients had malignancy. The validity results of endoscopic ultrasonography-fine needle aspiration in comparison to histopathology findings were sensitivity (87%), specificity (78.6%), +ve predictive value (76.9%), -ve predictive value (88%) and accuracy (82.3%).Conclusions: Endoscopic Ultrasonography-Fine Needle Aspiration is an appropriate diagnostic choice for suspected gastrointestinal tumors.

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Section: Discussionsupporting

confidence: 92%

Role of Endoscopic Ultrasound Guided Fine Needle Aspirate for Evaluating Lesions in or Adjacent to Gastrointestinal Tract: A Single Tertiary Care Center Experience

2020

MLU

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“…2 Histopathological evaluation is the gold standard for early detection of GI malignancies. 17 Present study was carried on 161 cases of GI Male to female ratio was 1.4:1 which was similar to finding of Ekta et al, where male to female ratio was 1.33:1 in malignant cases. 4 Thakur et al had observed a much higher 1.7:1 male female ratio.…”

Section: Discussionsupporting

confidence: 90%

Gastrointestinal Malignancies: An Eight Years Experience

Goyal

Sedhain

Rai

et al. 2021

J Coll Med Sci-Nepal

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Background: Gastrointestinal malignancy constitutes a significant cancer burden in terms of mortality. They are most often detected late due to hidden location and lack of symptoms. This study was undertaken with an aim to see age and site distribution, histopathological spectrum, histologic grade and pathologic stage at presentation and to find correlation between histologic grade and pathologic stage at presentation. Methods: This retrospective chart review was carried on 161 cases of GI malignancies received in Department of Pathology of College of Medical Sciences and Teaching Hospital during a time period of 8 years from January 2012 to December 2019. Results: Age of the patients ranged from 16 to 93 years with a mean±SD of 57.3±16.3 years with maximum 36 (22.4%) cases in 51-60 years age group and a male female ratio of 1.4:1. 29 (18.0%) cases were seen at or below 40 years of age. Stomach was the most common site involved in 69 (42.9%) cases. Majority, 136 (84.5%) cases were adenocarcinoma. Majority, 48 (35.3%) cases of adenocarcinoma were Grade 2. Most 31 (45.0%) cases were Stage III at presentation. There was no statistical significant association between histologic grade and pathologic stage (p = 0.073). Conclusion: GI malignancy constitutes a significant cancer burden. Younger individuals are also considerably affected denoting a need of high degree of suspicion. Stomach was the most common site involved. Adenocarcinoma was the most common histological type. There was no association between histologic grade and pathologic stage at presentation (p > 0.05).

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“…In a study by Thakur RY et al in 2016 it was observed that 68% of digestive tract malignancies among females were colorectal adenocarcinomas. 20 The mean age for colorectal cancer was 56 years. Adenocarcinoma was the most common histopathological type of malignancy in the colon and rectum accounting for 67% of these cases.…”

Section: Resultsmentioning

confidence: 99%

“…22 Another study from Maharashtra reported similar findings with adenocarcinoma (50%) being the commonest gastric malignancy followed by equal percentage of signet ring cell and mucinous adenocarcinoma (25%). 20 Oral Cavity and Oropharynx: Oral cavity & oropharynx was the third most common site of malignancies. These were all squamous cell carcinomas.…”

Section: Resultsmentioning

confidence: 99%

Recent trends in histopathological spectrum of malignancies among females in western Maharashtra

Gore¹,

Dey²,

Kumar³

et al. 2020

IJPO

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Introduction: Aim of this study is to evaluate the histopathological spectrum of female malignancies with a motive to understand the prevalent trends of this complex disease. Materials and Methods: This was a retrospective and prospective study carried over a period of three years. All female patients with histopathologically confirmed malignancies were included in the study. Result: Total of 1016 cases of malignant lesions were included of which majority were in age group of 40 to 69 years. Breast was the commonest site for primary malignancies followed by cervix. Oropharyngeal squamous cell carcinoma ranked third while colorectal carcinomas emerged as the fourth most prevalent malignancy followed by ovarian cancer. Infiltrating duct carcinoma of the breast was the commonest histopathologic type of malignancy. Majority of the cervical and oropharyngeal cancers were squamous cell type. Colorectal adenocarcinoma was the most common malignancy in the GI tract. Among skin malignancies, squamous cell carcinoma were the most prevalent type followed by basal cell carcinoma and malignant melanoma. Adenocarcinomas were the commonest lung lesions while papillary carcinoma was the most prevalent thyroid malignancy. Transitional cell cancers were the most frequent urinary bladder lesions while renal cell carcinomas were most common kidney malignancy. Conclusion:In spite of many recently developed diagnostic modalities; histopathological examination remains the gold standard for the diagnosis of malignant lesions. Hospital based Cancer Registries should be established since they provide data which can prove to be an invaluable tool to understand and plan effective remedial measures in the battle against cancer.

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Clinico Histopathological Overview of GIT Lesions in a Rural Hospital

Cited by 8 publications

References 0 publications

Role of Endoscopic Ultrasound Guided Fine Needle Aspirate for Evaluating Lesions in or Adjacent to Gastrointestinal Tract: A Single Tertiary Care Center Experience

Role of Endoscopic Ultrasound Guided Fine Needle Aspirate for Evaluating Lesions in or Adjacent to Gastrointestinal Tract: A Single Tertiary Care Center Experience

Gastrointestinal Malignancies: An Eight Years Experience

Recent trends in histopathological spectrum of malignancies among females in western Maharashtra

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