Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria

Bakari, AG; Afolabi, OA; Adoga, Adeyi A; Kodiya, Aliyu Mohammed; Ahmad, Babagana M

doi:10.1186/1756-0500-3-186

Cited by 62 publications

(109 citation statements)

References 12 publications

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“…Nasal polyps had slight predilection for males in our study, (male:female ratio of 1.3:1). It was similar to various studies [27,28] but a study from Nigeria showed female preponderance (M:F = 1:1.2) [30]. There was a marked gender difference in controls (M:F = 10.6:1).…”

Section: Resultssupporting

confidence: 91%

Detection of Helicobacter pylori in Nasal Polyps

Bansal

Sharma

Agarwal

et al. 2016

Head and Neck Pathol

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To detect the presence of Helicobacter pylori in nasal polyps. A case-control study was conducted enrolling 35 patients with nasal polyps (cases) and patients undergoing septoplasty (controls). Fresh tissue samples were used for urea broth test and imprint cytology, while formalin fixed tissue sections were used for morphology, special stains and immunohistochemistry for H. pylori. Fresh stool samples from both groups were tested to correlate the gastrointestinal status. H. pylori was detected in 40.0 % (14/35) of cases and 8.5 % of controls (3/35) (p = 0.004) by immunohistochemistry. Amongst cases, eight were positive with urea broth test, six with imprint cytology (Giemsa stain), three with H & E, and nine with modified McMullen's stain. Hyperplasia of the lining epithelium and lymphoid aggregates were significantly noticed in nasal polyps positive for H. pylori. Stool antigen test was positive in subjects who were positive for H. pylori in the nasal mucosa. There appears to be an association between H. pylori and nasal polyps. Immunohistochemistry is more sensitive and specific method to detect H. pylori.H. pylori induced inflammatory tissue reaction pattern indicates a possible causal association. Further studies are needed to prove the causal relationship between H. pylori and nasal polyps.

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Section: Resultssupporting

confidence: 91%

Detection of Helicobacter pylori in Nasal Polyps

Bansal

Sharma

Agarwal

et al. 2016

Head and Neck Pathol

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“…Bakari et al in 2010 had reported a peak incidence of 33years. 7 This seems to be accordance with our study.…”

Section: Resultssupporting

confidence: 83%

Study of heterogeneity of sino-nasal lesions in urban population of north Kolkata and its fringes- a 5-year retrospective analysis: experience of a tertiary care centre

Bhattacharyya¹,

Das²,

Mukherjee³

et al. 2017

Int J Res Med Sci

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Background: Lesions of the nasal cavity and paranasal sinuses form a single functional unit as both of these are affected by common pathological processes. Accurate diagnosis and early treatment can significantly reduce the morbidities associated with these lesions. This study aims at portraying the morphological diversions of sinonasal lesions that is commonly encountered in populations of north Kolkata and its fringes. The multitude of histopathological variations of the sinonasal masses intrigues us histopathologists not only from academic point of view but also guides clinicians regarding treatment and prognosis.Methods: A retrospective study conducted in the Department of Pathology from May 2012 to April 2017.Results: Total 429 cases were assessed during this period out of which maximum cases were found in the age group of 31- 40years. Most cases were diagnosed with nasal polyps. The rare histopathological types were ameloblastoma, paraganglioma, Schwanoma, neurofibroma, inflammatory myofibroblastic tumor, sinonasal hemangiopericytoma, adenoid cystic carcinoma, low grade mucoepidermoid tumor, malignant peripheral nerve sheath tumor.Conclusions: Both neoplastic and non-neoplastic sino nasal lesions may present with indistinguishable features, leading to a delay in proper diagnosis and treatment. So, any tissue after surgical removal should be send for histopathological diagnosis without unnecessary delay to prevent further complications.

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“…Bakari et al, reported a peak incidence of 33 years. 20 Larsen et al, reported similar results of 252 danish patients. They observed nasal polyposis most commonly in patients who were 40-60 years old.…”

Section: Age and Sex Distributionsupporting

confidence: 71%

Comparative study of conventional versus microdebrider assisted endoscopic sinus surgery in sinonasal polyposis

Ghera

Munjal

Chopra

2016

Int J Otorhinolaryngol Head Neck Surg

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INTRODUCTIONSinonasal polyp refers to edematous projections of nasal mucosa extending through nasal cavity and paranasal sinuses. Prevalence is 4% in general population. 1 Functional endoscopic sinus surgery, conventional or with powered instruments is standard surgical modality in sinonasal polyposis refractive to medical therapy. Microdebriders are the most commonly used powered instruments in endoscopic sinus surgery and continues to evolve in rhinologic surgery. 2 The aim of study was to evaluate the utility of microdebrider in endoscopic sinus surgery versus conventional instruments and to compare ABSTRACT Background: Functional endoscopic sinus surgery, conventional or with powered instruments is the standard surgical modality in sinonasal polyposis refractive to medical therapy. The recent modality, microdebrider assisted endoscopic sinus surgery offers better therapeutic approach for patients when compared to endoscopic sinus surgery with the conventional instruments. The objective was to evaluate the utility of microdebrider in endoscopic sinus surgery versus conventional instruments and to compare the intraoperative and postoperative results in both the methods. Methods: A prospective, randomized, comparative study was conducted on 30 patients with bilateral sinonasal polyposis. The subjects were selected by applying all the inclusion and exclusion criteria and divided into two groups i.e. the right and left side of nose were operated and compared for efficacy of microdebrider and conventional instruments. Each patient served as his or her own control. This study emphasizes the utility of microdebrider. It compares the intraoperative and postoperative results in the conventional and microdebrider assisted endoscopic sinus surgery. Results: The intraoperative mean blood loss and duration of surgery were significantly higher in the conventional group (p-value <0.001) as compared to microdebrider group. Postoperative symptom and endoscopy scores (discharge, scarring, crusting and polyp recurrence) were significantly higher in the conventional group (p-value <0.001) as compared to the microdebrider group in 6 months follow up. Conclusions: Microdebriders are more effective as compared to conventional endoscopic sinus surgery due to lesser intraoperative bleeding (relatively bloodless) and duration of surgery, better postoperative endoscopic and symptom scores, combine cutting and suction in a single tool, enabling accurate and precise tissue removal without damaging the surrounding mucosa , less scarring/synechiae, fewer complications.

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Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria

Cited by 62 publications

References 12 publications

Detection of Helicobacter pylori in Nasal Polyps

Detection of Helicobacter pylori in Nasal Polyps

Study of heterogeneity of sino-nasal lesions in urban population of north Kolkata and its fringes- a 5-year retrospective analysis: experience of a tertiary care centre

Comparative study of conventional versus microdebrider assisted endoscopic sinus surgery in sinonasal polyposis

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