Clinico-Pathomorphological Features of Papillary Thyroid Microcarcinoma Accompanied by Chronic Lymphocytic Thyroiditis

Abstract

It was analyzed and identified clinico-pathomorphological features of papillary thyroid microcarcinoma (PTMC) concurrent with chronic lymphocytic thyroiditis (CLT). We found PTMC associated with CLT to have smaller size of carcinoma, significantly lower invasion to lymphatic vessels and capsule of thyroid gland as well as lower rate of metastases to local lymphonodules. Our results lead to conclusion that PTMC associated with CLT has lower level of biological aggressiveness. From these data we also hypothesize that CLT with may serve as a positive prognostic factor for patients with PTMC.