Clinicohistopathological features and molecular markers of breast cancer in a group of patients at the Yaoundé General Hospital -Cameroon

Ngowa, Jean Dupont Kemfang; Ebune, J. L.; Ngassam, Anny; Atangana, J.; Kabeyene, A.; Kasia, Jean Marie

doi:10.1007/s12558-015-0380-y

J Afr Cancer

2015

DOI: 10.1007/s12558-015-0380-y

|View full text |Cite

Clinicohistopathological features and molecular markers of breast cancer in a group of patients at the Yaoundé General Hospital -Cameroon

Jean Dupont Kemfang Ngowa

J. L. Ebune

Anny Ngassam

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Immuno-Histochemical Profile of Breast Cancers at the General Hospital of Douala-Cameroon

Guy,

Junie,

Tatah

et al. 2023

OJOG

View full text Add to dashboard Cite

Introduction: The aim of the study was to describe the immunohistochemical aspects of breast cancers at Douala General Hospital, Cameroon. Methodology: This was a descriptive study with retrospective data collection, conducted from January 1 st 2010 and December 31 st 2019. It was focused on histologically proven breast cancers followed up at Douala General Hospital. Results: We collected 285 cases of breast cancer, all female, representing an annual frequency of 28.5 cases. The mean age of the patients was 48 ± 13 years. The most frequent histological form was infiltrating ductal carcinoma (83.9%), with grade II predominating (38.6%). Immunohistochemical analyses were performed on 89 patients (31.23%). The triple-negative subtype was the most common class (35.95%), followed by Luminal A (32.60); Human Epidermal Receptor 2-class and Luminal B tumors were observed at a frequency of 13.48% each. Treatment consisted mainly of surgery (78.60%) combined with chemotherapy (65.97%) and/or radiotherapy (63.16%). Hormonal treatment was used in only 10.18% of patients. Targeted therapy was exceptional (4%). Conclusion: Triple-negative phenotype is the most common. However, potentially hormone-sensitive tumors account for almost half of all patients, who are relatively young. Individualized treatments are rare. It is important to systematize these analyses for all breast cancers, with a view to appropriate management in our environment.

show abstract

Immuno-Histochemical Profile of Breast Cancers at the General Hospital of Douala-Cameroon

Guy,

Junie,

Tatah

et al. 2023

OJOG

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Clinicohistopathological features and molecular markers of breast cancer in a group of patients at the Yaoundé General Hospital -Cameroon

Cited by 1 publication

References 10 publications

Immuno-Histochemical Profile of Breast Cancers at the General Hospital of Douala-Cameroon

Immuno-Histochemical Profile of Breast Cancers at the General Hospital of Douala-Cameroon

Contact Info

Product

Resources

About