“…5,26-30 The infiltrate
consists of small and mediumsized lymphocytes with irregular nuclei and formation of
Pautrier's microabscesses inside the follicular epithelium. 33,34 The follicles classically show a corneous plug and, at times, epithelial mucin
degradation with variable intensity. 30-33
…”
Section: Mycosis Fungoides Clinical Variants Described In the "Who-ementioning
confidence: 99%
“…7 However, it is no longer accepted as an example of pagetoid reticulosis and
seemingly represents generalized forms of classic MF or cytotoxic, epidermotropic
CD8 + CTCL of severe evolution. 8,22,34
…”
Section: Mycosis Fungoides Clinical Variants Described In the "Who-ementioning
confidence: 99%
“…5,22,31,34 The cellular proliferation rate estimated by Ki-67 immunostaining is higher
than 30% in pagetoid reticulosis and lower than 10% in MF, but it still has a good
prognosis. 5,22,31,34
…”
Section: Mycosis Fungoides Clinical Variants Described In the "Who-ementioning
This paper reviews the diagnostic and classificatory concepts of mycosis fungoides
and Sézary syndrome in light of the latest normative publications. It
describes the great variability of the clinical expression of mycosis fungoides in
its early stages as well as the histopathological and immunohistochemical aspects
that help with diagnosis. The diagnostic criteria required for characterizing
Sézary syndrome and the staging system used for both mycosis fungoides and
Sézary syndrome are described.
“…5,26-30 The infiltrate
consists of small and mediumsized lymphocytes with irregular nuclei and formation of
Pautrier's microabscesses inside the follicular epithelium. 33,34 The follicles classically show a corneous plug and, at times, epithelial mucin
degradation with variable intensity. 30-33
…”
Section: Mycosis Fungoides Clinical Variants Described In the "Who-ementioning
confidence: 99%
“…7 However, it is no longer accepted as an example of pagetoid reticulosis and
seemingly represents generalized forms of classic MF or cytotoxic, epidermotropic
CD8 + CTCL of severe evolution. 8,22,34
…”
Section: Mycosis Fungoides Clinical Variants Described In the "Who-ementioning
confidence: 99%
“…5,22,31,34 The cellular proliferation rate estimated by Ki-67 immunostaining is higher
than 30% in pagetoid reticulosis and lower than 10% in MF, but it still has a good
prognosis. 5,22,31,34
…”
Section: Mycosis Fungoides Clinical Variants Described In the "Who-ementioning
This paper reviews the diagnostic and classificatory concepts of mycosis fungoides
and Sézary syndrome in light of the latest normative publications. It
describes the great variability of the clinical expression of mycosis fungoides in
its early stages as well as the histopathological and immunohistochemical aspects
that help with diagnosis. The diagnostic criteria required for characterizing
Sézary syndrome and the staging system used for both mycosis fungoides and
Sézary syndrome are described.
“…WK disease, first described in 1939, usually presents with a slow growing, solitary patch, or plaque on the extremities . The disease has been reported to have a predilection for middle‐age males.…”
Woringer-Kolopp (WK) is a rare subtype of cutaneous T-cell lymphoma (CTCL) with limited treatment options. Bexarotene gel is a topical retinoid used in the treatment of CTCL. This report describes three female patients (mean age 66 years) with WK disease who had an effective treatment response to bexarotene 1% gel. This treatment could provide a safe alternative to other current treatment modalities which have higher risks of potential adverse effects and lack of access to other conventional treatments such as light therapy.
“…Localized pagetoid reticulosis (PR), also known as Woringer–Kolopp disease, is a rare variant of mycosis fungoides or cutaneous T‐cell lymphoma . We report a case of PR treated with ablative fractional laser‐assisted photodynamic therapy (AFXL‐assisted PDT).…”
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