Clinicopathologic profile of normocomplementemic and hypocomplementemic urticarial vasculitis: a study from South India

Dincy, C V P; George, Renu; Jacob, Molly; Mathai, E; Pulimood, Susanne; Eapen, E P

doi:10.1111/j.1468-3083.2007.02641.x

Cited by 50 publications

(87 citation statements)

References 14 publications

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“…Gastrointestinal and neurologic involvement can also be seen [50,52]. Antinuclear antibody (ANA) positivity has also been reported in up to 78% of HUV patients [52,54].…”

Section: Urticarial Vasculitismentioning

confidence: 95%

“…The most common systemic manifestations are in the joints, kidneys, and lungs [52,54]. Gastrointestinal and neurologic involvement can also be seen [50,52]. Antinuclear antibody (ANA) positivity has also been reported in up to 78% of HUV patients [52,54].…”

Section: Urticarial Vasculitismentioning

confidence: 98%

“…However, there is a propensity to more severe multi-organ involvement in HUV patients [48]. The most common systemic manifestations are in the joints, kidneys, and lungs [52,54]. Gastrointestinal and neurologic involvement can also be seen [50,52].…”

Section: Urticarial Vasculitismentioning

confidence: 99%

“…Leukocytoclastic vasculitis of the small dermal vessels characterized by a neutrophilic perivascular iniltrate, the typical indings for UV, is observed in fully developed lesions. Additionally, neutrophil fragmentation, nuclear dust, erythrocyte extravasation, and ibrin deposition in and around the vessels are observed [50,52].…”

Section: Urticarial Vasculitismentioning

confidence: 99%

“…Steroid-sparing agents are used in the treatment to avoid the side efects of long-term corticosteroids. Dapsone, colchicine, hydroxychloroquine, mycophenolate mofetil, interferon-alpha, cyclosporine A, azathioprine, cyclophosphamide, rituximab, intravenous immunoglobulins, anakinra, and plasmapheresis are treatment agents that can be used alone or in combination with corticosteroids [50][51][52].…”

Section: Urticarial Vasculitismentioning

confidence: 99%

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Urticarial Syndromes

Gökalp¹,

Bulur²

2017

A Comprehensive Review of Urticaria and Angioedema

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Urticaria is a common dermatological condition that can occur in acute and chronic forms. Common urticaria is generally easy to diagnose; however, urticarial syndromes should be considered in cases where lesions persist for greater than 24-36 h, the location of lesions has bilateral symmetry, urticarial lesions are accompanied by additional elementary lesions, and/or the patient presents with additional systemic symptoms. Additionally, urticarial syndromes should be considered for patients with typical urticarial lesions that do not respond to systemic antihistamine treatment. Hyperpigmentation or bruising can be observed following resolution of urticarial syndromes. Many cutaneous and systemic diseases can cause urticarial syndromes. Systemic causes of urticarial syndromes can afect multiple organ systems and may be accompanied by systemic symptoms such as fever, asthenia, and arthralgia. Clinicopathologic correlation is essential for the accurate diagnosis of urticarial syndromes. In this chapter, cutaneous and systemic etiologies of urticarial syndromes are reviewed.

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“…Gastrointestinal and neurologic involvement can also be seen [50,52]. Antinuclear antibody (ANA) positivity has also been reported in up to 78% of HUV patients [52,54].…”

Section: Urticarial Vasculitismentioning

confidence: 95%

Section: Urticarial Vasculitismentioning

confidence: 98%

Section: Urticarial Vasculitismentioning

confidence: 99%

Section: Urticarial Vasculitismentioning

confidence: 99%

Section: Urticarial Vasculitismentioning

confidence: 99%

See 3 more Smart Citations

Urticarial Syndromes

Gökalp¹,

Bulur²

2017

A Comprehensive Review of Urticaria and Angioedema

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Cutaneous Vasculitis

Levell

Mukhtyar

2016

Rook's Textbook of Dermatology, Ninth Edition

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Overview Vasculitis is usually a multisystem disorder that presents in a myriad of ways. Diagnosis is based on a detailed history and careful examination. Patients may present to different specialties and their care should be led by a multidisciplinary team involving physicians with a specialist interest in vasculitis. Vasculitis can be classified by aetiology or by calibre of the vessel involved. The accepted nomenclature was defined by an international consensus meeting held in 2012; cutaneous vasculitides are considered under the umbrella of ‘single organ vasculitis’, although the classification has been expanded in this chapter. Ill‐defined entities that do not have an identified pathological basis have not been included. It should be recognized that names and classifications will change in the future with greater understanding of the underlying mechanisms of disease. The treatment of primary vasculitis involves immunosuppression. The balance between disease severity and adverse effects of treatment requires expertise and experience in management of these rare conditions. Secondary vasculitis may be due to infection, drugs, malignancy or inflammatory disease. Treating the underlying condition may resolve the vasculitis.

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