Clinicopathologic spectrum of specific cutaneous lesions of disseminated coccidioidomycosis

Coccidioidomycosis: A review and update

“…129,131 Skin lesions may be solitary or multiple and may ulcerate (Fig 6). Even after resolution of other symptoms, disseminated skin lesions may rarely become chronic (Figs 7 and 8).…”

Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Associated With Pulmonary Coccidioidomycosis

“…Organismspecific lesions contain Coccidioides, which may be identified in skin biopsy specimens by routine histochemical stains, special fungal stains, or fungal cultures. 17 Reactive cutaneous lesions, which contain no viable organisms, result from the immune response of the host. Sweet syndrome has been described as a reactive manifestation of coccidioidomycosis in only 1 previous case.…”

“…9 A variety of cutaneous signs may be seen in association with coccidioidomycosis. [16][17][18][19] Both reactive and organism-specific lesions may occur (Table). Organismspecific lesions contain Coccidioides, which may be identified in skin biopsy specimens by routine histochemical stains, special fungal stains, or fungal cultures.…”

Coccidioidomycosis

“…17.6). Less commonly, erythema multiforme and erythema sweetobullosum are seen [38,39]. Migratory arthralgias are common; the triad of fever, erythema nodosum, and arthralgias has been referred to as "desert rheumatism."…”