Clinicopathological assessment of chronic hyperplastic candidasis

Abstract

Background: Chronic hyperplastic candidiasis is the least common type of oral candidiasis. The diagnosis, long-term treatment, and prognosis of this potentially malignant oral condition are still currently unclear. Objective: the aim of this study is to analyze the demographic features and clinical characteristics of oral chronic hyperplastic candidiasis. Materials and Methods: A retrospective analysis was performed on blocks and case sheets of patients who were diagnosed with chronic hyperplastic candidiasis in the archives of Oral and Maxillofacial Pathology at the College of Dentistry/University of Baghdad. Demographic and clinical characteristics were analyzed. Results: twenty-one cases with chronic hyperplastic candidiasis were collected and reviewed. Buccal mucosa was the most affected sites. Regarding the clinical features, lesions color frequently presented as white plaque. Regarding clinical diagnosis, leukoplakia was noted the highest one among other previous diagnosis. Conclusions: Older adults are the mostly affected age group by chronic hyperplastic candidiasis with slight male predilection. White plaque is the most presented clinical feature with buccal mucosa being the most affected oral site.

Antimicrobial photodynamic therapy using a low-power 650 nm laser to inhibit oral Candida albicans activity: an in vitro study

“…The oral cavity harbors a variety of microorganisms, including viruses, bacteria, fungi, and protozoa, creating an environment suitable for the proliferation of several microbial species, which, under certain conditions, can become pathogenic [ 1 , 2 ]. Among these, Candida infections in the oral mucosa have become increasingly prevalent.…”

In vitro Investigation the Antifungal and 940 nm Diode Laser Effects on Inhibition of Candida Albicans Isolated from Oral Cavity

“…Oral candidiasis is caused by a fungal infection called Candida albicans, which accounts for 60-70% of all cases (Hussain and Al-Drobie, 2022). Non-pathogenic Oral candidiasis could be caused by the yeast Candida albicans, which was a common member of the oral microbiota.…”