Clinicopathological Characteristics of Remnant Gastric Cancer After a Distal Gastrectomy

Abstract

An annual follow-up endoscopic examination an after initial gastrectomy may be related to improving the prognosis of patients with RGC.

Surgical Resection of Remnant Gastric Cancer Following Distal Gastrectomy: A Retrospective Clinicopathological Study

“…6,12,17,19,[25][26][27] In our study, as for other previous studies, the interval between first gastrectomy and the second surgery of RGC after benign disease was longer than that after malignant disease. 5,6,[16][17][18]22,26,28 RGC after benign disease is considered to originate from the exposure to duodenogastric reflux of bile and pancreatic There is an overlap in the number of organs with combined resection and recurrence M mucosa, SM submucosa, MP muscularis propria, SS subserosa, SE serosa-exposed, SI serosa-infiltrating a Statistically significant fluid. 6,16,[29][30][31][32][33] In contrast, RGC after malignant disease is considered to stem from mucosal changes leading to cancer, such as atrophic changes and intestinal metaplasia.…”

“…In several other reports, RGC curative resection rates were 50-90 %. 5,7,10,17,19,20,26,40 The rates of combined other organ resection of other organs were 27.9 % in our study. In some other reports, the rates of combined resection of other organs were 40-70 %.…”

“…6,16,[29][30][31][32][33] In contrast, RGC after malignant disease is considered to stem from mucosal changes leading to cancer, such as atrophic changes and intestinal metaplasia. 6,26,27,34 It is probable that any pre-existing precancerous condition is strongly related to malignant transformation as compared with duodenogastric reflux. In addition, the denervation by primary gastric surgery for gastric cancer might promote carcinogenesis in the remnant stomach.…”

Tumors Arising at Previous Anastomotic Site may have Poor Prognosis in Patients with Gastric Stump Cancer Following Gastrectomy

“…This surveillance program commencing 1 year after the gastrectomy for at least 10 years is in line with the other reports. 7,34 Conclusion Earlier detection and the simultaneous, careful observation of anastomotic site are important considerations for improving long-term prognosis of GSC. Thorough follow-up programs should be conducted, continuing up to 10 years after initial gastrectomy and taking account of the potentially different latency periods for GSC development between patients with previous benign disease and those with malignant disease.…”

The pattern of lymph node metastasis and the suitability of 7th UICC N stage in predicting prognosis of remnant gastric cancer

“…The incidence of RGC was 1-5% in previous reports (Firat et al 2009;Ojima et al 2010;Tanigawa et al 2010). Because no typical symptoms and signs were available at early stage, RGCs were often reported to be detected at advanced stages and had higher LN metastasis rate in comparing with conventional gastric cancer (Tanigawa et al 2010;Elliot Newman et al 1997).…”